Publications by authors named "Lu-Xia Wang"

Constructed in-plane heterojunction contacts between the semiconducting 2H phase (as the channel) and the metallic 1T' phase (as the electrode), two-dimensional (2D) transition metal dichalcogenide (TMD) field-effect transistors (FETs) have received much recent attention because they significantly reduce contact resistance. In this paper, quantum transport simulation is done to study and predict the electronic states and contact properties of the 2H-MoS/1T'-MX (WS, TaSe, NbSe, MoSe, TaS, and NbS) in-plane heterojunctions. It is found that the interfacial states are not obvious and the fluctuation of the average electron density at the 1T'/2H phase boundary is small for all 2H-MoS/1T'-MX heterojunctions.

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A series of (3-benzyl-5-hydroxyphenyl)carbamates were evaluated as new antibacterial agents. Several compounds showed potent inhibitory activity against sensitive and drug-resistant Gram-positive bacteria. The compounds are ineffective against all tested Gram-negative bacteria.

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ZTW-41, an indolizinoquinoline-5,12-dione derivative, was investigated for antibacterial activity against Gram-positive bacteria, especially methicillin-resistant (MRSA). In our study, the MICs (minimum inhibitory concentrations) of ZTW-41 against MRSA (MRSA,  = 200), methicillin-sensitive (MSSA,  = 100), (,  = 32), and ( = 32) were 0.25, 0.

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In our previous research, 9-bromo indolizinoquinoline-5,12-dione 1 has been found to be a good anti-MRSA agent. However, it had very low bioavailability in vivo possibly due to its low solubility in water. In order to obtain the derivatives with higher anti-MRSA activity and good water solubility, twenty eight bromo-substituted indolizinoquinoline-5,12-dione derivatives were synthesized in the present study.

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A series of 9-bromo-substituted indolizinoquinoline-5,12-dione derivatives was synthesized. Antimicrobial activity assessment indicates that compounds 1, 26, 27 and 28 exhibit strong activity against gram-positive bacterial strains, including Beta-hemolytic streptococcus CMCC32210, Staphylococcus aureus ATCC25923, Staphylococcus epidermidis ATCC12228, Enterococcus faecalis ATCC29212 and methicillin-resistant S. aureus ATCC43300 (MRSA).

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Objective: To study the clinical significance of virulence genes exo U and exo S of type III secretion system (TTSS) of Pseudomonas aeruginosa (PA).

Methods: One hundred and eighty-nine clinical isolates of PA were collected from five hospitals. The incidence of virulence genes exo U and exo S in PA were determined with PCR.

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Article Synopsis
  • The study aimed to evaluate the effectiveness of using a gene chip method to identify pathogens in blood cultures compared to conventional methods.
  • Blood samples were cultured and analyzed, showing that the gene chip method detected fewer positives than the conventional technique, with only about 69.77% agreement between the two methods.
  • The findings suggest that while the gene chip method has potential, it currently shows poor concordance with standard methods and needs enhancements for better accuracy.
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Objective: To investigate the frequencies of primary biliary cirrhosis (PBC)-specific autoantibodies, including antimitochondrial autoantibodies (AMA) M2, anti-gp210 and anti-Sp100, and to assess their point prevalence rates in a general adult population group in Guangzhou.

Methods: Eight thousand one hundred twenty-six adults (mean age 43.5+/-14.

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Objective: To study the anti-microbial resistance of Escherichia coli (E.coli) that caused infection in urogenital system.

Method: Anti-microbial susceptibility tests for 148 strains of E.

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Objective: To study the drug-resistance of Acinetobacter spp and observe whether antibiotic-beta- lactamase inhibitor complexing agent enhances the sensitivity of the drug-resistant bacteria to the antibiotics.

Methods: Susceptibility tests to the antibiotics were performed for 60 isolated strains of Acinetobacter spp with Kirby-Bauer (K-B) and Etest methods.

Results: The drug-resistance rate of the strains to cefoperazone, ampicillin, ticarcillin and piperacillin exceeded 55.

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