Publications by authors named "Lu-Jin Zhang"
Background: Lung adenocarcinoma (LUAD) is the leading histological subtype of lung cancer worldwide, causing high annual mortality. Tsvetkov et al. recently found a new form of regulated cell death, termed cuproptosis.
View Article and Find Full Text PDFDiagnostic value of circular free DNA for colorectal cancer detection.
World J Gastrointest Oncol
June 2023
Article Synopsis
- There is a critical need for a noninvasive and accurate method to detect colorectal cancer (CRC) in clinical settings.
- Researchers aimed to find a specific circular free DNA marker using digital polymerase chain reaction (dPCR) for early CRC diagnosis, involving a study with healthy controls and CRC patients.
- The biomarkers CEA and CAMK1D were evaluated, where CAMK1D showed a higher diagnostic capability, achieving an area under the curve (AUC) as high as 0.978 for early CRC detection, indicating strong sensitivity and specificity in differentiating between healthy individuals and CRC patients.