Publications by authors named "Lu-Chang Cao"

Background: Gastric cancer (GC) is the fifth most commonly diagnosed malignancy worldwide, with over 1 million new cases per year, and the third leading cause of cancer-related death.

Aim: To determine the optimal perioperative treatment regimen for patients with locally resectable GC.

Methods: A comprehensive literature search was conducted, focusing on phase II/III randomized controlled trials (RCTs) assessing perioperative chemotherapy and chemoradiotherapy in treating locally resectable GC.

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Article Synopsis
  • Cancer is a leading cause of death, especially with low 5-year survival rates for digestive tract cancers, and while chemotherapy is effective, it can be toxic and lead to resistance.
  • There is growing interest in natural drugs for cancer treatment due to their lower toxicity and potential to enhance the effectiveness of existing therapies like chemotherapy and radiotherapy.
  • Paris polyphylla (PPA), a natural medicinal plant, contains active components such as polyphyllin, C steroids, and flavonoids, which show promise in targeting various digestive tract cancers, and this paper reviews their mechanisms and research developments.
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Traditional Chinese medicine(TCM) is an important feature of cancer treatment in China. The methods to tap the advantages of TCM, reasonably evaluate and accurately apply Chinese patent medicines have become current research hotspots and difficulties. TCM takes syndrome differentiation and treatment as the core, with the characteristics of overall regulation and multi-targets efficacy.

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