Publications by authors named "Lu Xing-Ru"
Objective: To explore the efficacy of the quantitative parameter histogram analysis of intravoxel incoherent motion (IVIM) for different molecular prognostic factors of breast cancer.
Materials And Methods: A total of 72 patients with breast cancer who were confirmed by surgical pathology and underwent preoperative magnetic resonance imaging (MRI) were analyzed retrospectively. A region of interest (ROI) was drawn in each slice of the IVIM images.
Background: To investigate the value of 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (18F-FDG PET/MRI) in diagnosing local tumor invasion (T stage), evaluating regional lymph node involvement (N stage), and detecting distant metastasis (M stage) in breast cancer patients.
Methods: A comprehensive computer search and manual search were performed to select any potentially eligible studies that evaluated the diagnostic efficacy of 18F-FDG PET/MRI in the tumor-node-metastasis (TNM) staging of breast cancer. Data from the included studies were extracted to calculate the pooled sensitivity, specificity, and area under the curve (AUC) to evaluate the value of 18F-FDG PET/MRI in TNM staging.
Rationale And Objectives: To assess differences of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) parameters at different postcontrast time points (TPs), and to explore the predictive value of DCE-MRI parameters for axillary lymph node (ALN) metastasis of breast cancer.
Materials And Methods: A total of 107 breast cancer patients were included retrospectively, and 50 phases were collected on DCE-MRI for each patient. DCE-MRI parameters Ktrans, Kep, Ve, TTP, Peak, Washin, Washout, and AUC were extracted from the images at 67.
Article Synopsis
- The study investigates the effectiveness of contrast-enhanced magnetic resonance imaging (CEMRI) in detecting residual or recurrent hepatocellular carcinoma (HCC) in patients after undergoing transarterial chemoembolization (TACE).
- A systematic review and meta-analysis were conducted, analyzing 13 studies that included 721 nodules to evaluate the diagnostic accuracy of CEMRI.
- Results showed high pooled sensitivity (91%) and specificity (93%) for CEMRI, indicating it is a reliable diagnostic tool, especially in prospective studies.
Article Synopsis
- The report discusses the development of a new modified thrombin-binding aptamer (TBA) that incorporates anti-guanine bases and a loop-locked nucleic acid (LNA) to enhance binding to thrombin.
- Techniques like NMR, circular dichroic spectroscopy, and molecular modeling were used to analyze the three-dimensional structure of two G-quadruplexes formed by the modifications.
- The modifications not only improve the aptamer's stability and affinity for thrombin but also maintain strong inhibitory activity, suggesting that LNA modifications significantly enhance the aptamer's properties.
Background: Dual-source and 320-row computed tomography angiography (CTA) are increasingly used in diagnosing coronary in-stent restenosis (CISR).
Purpose: We sought to perform this meta-analysis to evaluate the diagnostic accuracy of dual-source computed tomography angiography (DSCTA) and 320-row CTA in detecting CISR when compared to invasive coronary angiography.
Material And Methods: Five scientific databases (PubMed, Embase, Scopus, The Cochrane Library, and Web of Science) were searched for research studies in which DSCTA and/or 320-row CTA were used as diagnostic tools for CISR, as recently as October 2017.
Article Synopsis
- - This meta-analysis evaluates the effectiveness of three-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA) in diagnosing intracranial aneurysms (IA) by analyzing data from 18 studies with a total of 3463 patients.
- - Results showed high diagnostic performance with sensitivity (89%) and specificity (94%), indicating that 3D-TOF-MRA is reliable for detecting IAs, especially in cases without subarachnoid hemorrhage.
- - The study concludes that 3D-TOF-MRA is an excellent tool for assessing intracranial aneurysms and could be an important option for managing patients with this condition.