Publications by authors named "Lu Niu"

Objectives: Accurate assessment of sleep quality is crucial for understanding sleep problems and their impact on health. This study analyzed the agreement between subjective sleep assessments and objective sleep monitoring in adolescents with mood disorders, aiming to provide a reliable methodological foundation for related research.

Methods: Adolescents with mood disorders were recruited from psychiatric outpatient clinics of three domestic hospitals.

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Under sustained global warming, Arctic climate is projected to become more responsive to changes in North Pacific meridional heat transport as a result of teleconnections between low and high latitudes, but the underlying mechanisms remain poorly understood. Here, we reconstruct subarctic humidity changes over the past 400 kyr to investigate the role of low-to-high latitude interactions in regulating Arctic hydroclimate. Our reconstruction is based on precipitation-driven sediment input variations in the Subarctic North Pacific (SANP), which reveal a strong precessional cycle in subarctic humidity under the relatively low eccentricity variations that dominated the past four glacial-interglacial cycles.

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Avoiding food waste has become an important global issue. Given the global impact of food waste and the profound influence of Generation Z on future development, it is crucial to guide them in cultivating awareness and behaviors to reduce food waste, thereby promoting sustainable development. Considering young consumers' specific characteristics and consumption environment, this study extended the Theory of Planned Behavior (TPB) framework by adding two constructs of moral self-identity and scarcity mindset.

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Objectives: We aimed to assess the quality of information regarding depression on Chinese websites and popular video platforms.

Methods: We conducted searches on website platforms (Baidu, Bing) and video platforms (Bilibili, Douyin) using search terms "depression", "depressive disorder", "depression treatment", "depressive anxiety", "depressed patient", and "depressive symptoms". We collected the first 50 results with each search term in each platform.

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Kidney-yang deficiency syndrome (KYDS) is characterized by a metabolic disorder stemming from neuroendocrine dysregulation, often associated with hepatic dysfunction. In traditional Chinese medicine, Linn. (BGZ) is commonly utilized for treating KYDS.

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In the present work the atomic, electronic and optical properties of two-dimensional graphene, borophene, and boron carbide heterojunction bilayer systems (Graphene-BC, Graphene-Borophene and Graphene-BC) as well as their constituent monolayers are investigated on the basis of first-principles calculations using the HSE06 hybrid functional. Our calculations show that while borophene is metallic, both monolayer BC and BC are indirect semiconductors, with band-gaps of 1.822 eV and 2.

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Automatic extraction of valuable, structured evidence from the exponentially growing clinical trial literature can help physicians practice evidence-based medicine quickly and accurately. However, current research on evidence extraction has been limited by the lack of generalization ability on various clinical topics and the high cost of manual annotation. In this work, we address these challenges by constructing a PICO-based evidence dataset PICO-DS, covering five clinical topics.

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Air pollution levels tend to be higher in urban areas than in surrounding rural areas, and this air pollution has a negative effect on human health. However, the spatiotemporal patterns of urban-rural air pollution differences and the determinants of these differences remain unclear. Here, we calculate the Urban Air Pollution Island (UAPI) intensity for PM and PM on a monthly, seasonal, and annual scale for 2273 cities in China from 2000 to 2020.

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This study used UPLC-TQ-MS technology to replicate a Henoch-Schonlein purpura(HSP) model in rats by administering warm drugs by gavage and injecting ovalbumin with Freund's complete adjuvant emulsion. The distribution differences and characteristics of eight major components(ferulic acid, caffeic acid, neochlorogenic acid, cryptochlorogenic acid, benzoyl oxypaeoniflorin, tracheloside, loganin, and paeoniflorin) in rat liver, lung, heart, spleen, and kidney tissues were determined after oral administration of the Liangxue Tuizi Mixture at a dose of 42 g·kg~(-1) in both normal physiological and HSP states at 0.5, 1, 2, 6, and 12 hours.

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Background: Health financing produce a broad range of healthy life expectancy (HLE) disparities. In West Africa, limited research exists on the association between health financing and HLE at ecological level during a consecutive period of time from the spatial perspectives. This study aimed to determine the existence, quantify the magnitude, and interpret the association between health financing and HLE.

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Background: West African countries experienced the highest under-5 mortality rate (U5MR), the lowest life expectancy, and the poorest economic development. This study aimed to explore the spatiotemporal trend of U5MR and spatial spillover effects of health resources and services to provide a basis for establishing health policies and international cooperative mechanisms in West Africa.

Methods: We retrieved data from the World Health Organization's Global Health Observatory, the United Nations Human Development Report, and the Global Burden of Disease Study 2019.

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The conversion of ethanol into high-valuable chemicals and H by photocatalytic process provides a sustainable approach to produce carbon-chain-prolonged chemicals and hydrogen energy. In this article, Ni-MOF-74 was added to fabricate the hierarchical CdS/NiS-N composites with an elevated specific surface area during the hydrothermal synthesis of CdS microsphere, and the Ni-MOF-74 facilitate the self-assemble growth of CdS and provide a source of Ni for the formation of NiS. The as-prepared photocatalyst was subjected to photocatalytic ethanol conversion, and the hierarchical composite material CdS/NiS-N (100) formed by adding 100 mg of Ni-MOF-74 exhibits the highest photocatalytic activity and stability in an ethanol aqueous solution with a water content of 10 %.

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The salt-tolerance of transgenic soybean cleared for environmental release was improved by stable over-expression of AhBADH gene from Atriplex hortensis, which was demonstrated through molecular analysis and field experiments. An effective strategy for increasing the productivity of major crops under salt stress conditions is the development of transgenics that harbor genes responsible for salinity tolerance. Betaine aldehyde dehydrogenase (BADH) is a key enzyme involved in the biosynthesis of the osmoprotectant, glycine betaine (GB), and osmotic balance in plants, and several plants transformed with BADH gene have shown significant improvements in salt tolerance.

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Alternative splicing (AS) is an important approach for pathogens and hosts to remodel transcriptome. However, tuberculosis (TB)-related AS has not been sufficiently explored. Here we presented the first landscape of TB-related AS by long-read sequencing, and screened four AS events (S100A8-intron1-retention intron, RPS20-exon1-alternaitve promoter, KIF13B-exon4-skipping exon (SE) and UBE2B-exon7-SE) as potential biomarkers in an in-house cohort-1.

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Objective: Promoting adolescent health is essential to achieving the goals of the Healthy China 2030 (HC 2030) initiative. As socioeconomic conditions improve and medical practices and disease patterns evolve, adolescent mortality rates and causes of death vary considerably. This study provides up-to-date data on adolescent mortality and causes of death in China, highlighting key areas of focus for investment in adolescent health.

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Hierarchical micro/nanostructures assembled from nanorods and nanosheets have become promising candidates for photocatalysis. In this work, a series of hierarchical Cd-Ni-MOF micro/nanostructures, assembled from nanosheets and nanorods, were fabricated a two-step solvothermal process involving the partial replacement of Ni with Cd in the Ni-MOF-74 structure. Different morphologies were obtained by considering different volume ratios of DMF and ethanol as the solvent during synthesis.

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Article Synopsis
  • Gut dysbiosis may influence immune functions and contribute to the development of Multiple Sclerosis (MS), and the treatment with Oxymatrine (OMAT) shows promise in addressing this issue.
  • OMAT was tested in EAE model mice, revealing it can restore gut flora diversity and impact metabolic pathways linked to energy and immune responses.
  • The treatment also improved the integrity of the blood-brain barrier and reduced inflammation, suggesting OMAT helps alleviate MS symptoms by correcting gut dysbiosis and enhancing gut-brain communication.
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TP53 is the most frequently mutated gene in muscle invasive bladder cancer (MIBC) and there are two gene signatures regarding TP53 developed for MIBC prognosis. However, they are limited to immune genes only and unable to be used individually across platforms due to their quantitative manners. We used 827 gene expression profiles from seven MIBC cohorts with varied platforms to build a pairwise TP53-derived transcriptome signature, 13 gene pairs (13-GPs).

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Background: Although () gene plays an important role in a number of biological processes, such as inflammation, its function and mechanism in ulcerative colitis (UC) remain unknown.

Methods: The UC model was established by feeding mice with 3.5% dextran sulfate sodium (DSS).

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Article Synopsis
  • The study used UPLC-TQ/MS to analyze 8 active components from Psoraleae Fructus in various tissues of normal and LPS-induced model rats after administering an ethanol extract.
  • It found that the distribution of these components varied significantly across different tissues, with higher concentrations in the liver and kidney compared to the spleen, heart, and lung.
  • Notably, the LPS-induced model rats showed higher levels of psoralen and increased absorption of psoralenoside and isopsoralenoside in liver tissue, suggesting a potential link to liver injury.
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Background: Exposure to tobacco imagery in films can result in tobacco use among adolescents and young adults. Efforts have been made to limit tobacco imagery in films in China. Our study investigates the level and trend of tobacco imagery in popular films in China from 2001 to 2020.

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