Publications by authors named "Lu Da Feng"
Xingnaojing injection (XNJ) is the only Chinese herbal injection approved for both intracerebral hemorrhage and ischemic stroke (IS) first-aid on ambulances in China; many systematic reviews (SRs) and meta-analyses (MAs) of XNJ on stroke have been published. The purpose of this research was to evaluate and summarize the current evidence on XNJ for IS. A comprehensive search was conducted for SRs and MAs of XNJ on IS in seven databases up to January 1, 2021.
View Article and Find Full Text PDFRadix Sophorae flavescentis versus no intervention or placebo for chronic hepatitis B.
Cochrane Database Syst Rev
April 2019
Article Synopsis
- Hepatitis B virus (HBV) can lead to severe liver issues and associated health risks, especially in people also infected with HIV or other hepatitis types, creating significant health and economic burdens.
- Radix Sophorae flavescentis is an herbal remedy believed to alleviate symptoms and inhibit HBV's replication, but its actual effects on patient outcomes haven't been thoroughly studied.
- The objective of the study is to determine the benefits and potential harms of Radix Sophorae flavescentis compared to a placebo or no treatment for patients with chronic hepatitis B, through a comprehensive review of existing clinical trials.
Error Matrix Tool to Overview the Validity of Evidence on Radix for Chronic Hepatitis B.
J Altern Complement Med
September 2019
Article Synopsis
- A visual error matrix tool was introduced to assess the validity of evidence for Radix in chronic hepatitis B, aiming to enhance clinical trial design and evidence quality.
- The analysis included 6 meta-analyses and 28 randomized clinical trials, revealing critical issues such as systematic errors at low quality and high risk of bias in randomized trials.
- Key findings indicated significant random errors for all-cause mortality and adverse events, alongside design errors related to participant selection and outcome misuse, highlighting the need for improved research methodologies.
Background: Therapy of nourishing kidney has been used for treating memory deficits of Alzheimer's disease (AD) for thousands of years based on traditional Chinese medicine. However, we found the therapy of dredging the bowels could alleviate both memory deficits and mental symptoms of AD in clinic.
Objective: To determine whether the therapy of dredging the bowels could enhance the neuroprotective effect of nourishing kidney herbs for treating AD rats, and to explore the underlying mechanism of the combination of nourishing kidney and dredging the bowels (NKDB) herbs.