Publications by authors named "Low G"

Purpose: To assess the effects of bladder fullness and lower uterine contractions ultrasound on transabdominal and transvaginal cervical length measurements at the mid-trimester fetal anomaly scan (FAS).

Methods: Transabdominal and transvaginal cervical length measurements from 925 mid-trimester FAS examinations were retrospectively analysed. Images were assessed for lower uterine contraction and bladder fullness using a novel qualitative assessment.

View Article and Find Full Text PDF

Purpose: The O-RADS malignancy risk stratification of typical ovarian dermoid cysts by using a 10 cm threshold is based on expert consensus rather than analysis of objective clinical data. This comprehensive scoping review consolidated all currently available studies evaluating typical benign ovarian dermoid cyst size and risk for malignant transformation.

Methods: A systematic review of MEDLINE, Embase, Scopus and the Cochrane library was performed from inception to January 14, 2024, using PRISMA-ScR guidelines.

View Article and Find Full Text PDF

Inferior vena cava (IVC) leiomyosarcomas are rare smooth muscle neoplasms that account for 0.5% of adult soft tissue sarcomas. They present with nonspecific symptoms and have poor prognosis.

View Article and Find Full Text PDF

Background And Objective: Accurate severity assessment in acute asthma is vital to guide patient management and disposition. End-tidal carbon dioxide (EtCO) has been proposed as a real-time measure for this purpose. This study aimed to systematically review literature on EtCO measurement in assessing the severity of acute asthma exacerbations.

View Article and Find Full Text PDF

Purpose: The current ACR and American College of Obstetricians and Gynecologists guidelines recommend a ≤4-mm endometrial thickness threshold for excluding endometrial cancer in symptomatic postmenopausal patients. This systematic review and meta-analysis aims to re-evaluate the optimal endometrial thickness threshold on imaging for excluding cancer in symptomatic postmenopausal patients.

Materials And Methods: A systematic search of MEDLINE, EMBASE, Cochrane Library, and Scopus from inception to October 2023 was performed in addition to a gray literature search.

View Article and Find Full Text PDF

To review the findings of a multiparametric MRI (the "liver triple screen") solution for the non-invasive assessment of liver fat, iron, and fibrosis in patients with chronic liver disease (CLD). A retrospective evaluation of all consecutive triple screen MRI cases was performed at our institution over the last 32 months. Relevant clinical, laboratory, and radiologic data were analyzed using descriptive statistics.

View Article and Find Full Text PDF
Article Synopsis
  • Anal fissures are a painful condition linked to tightness in the anal sphincter, leading to poor healing; various treatments exist, with a preference for preserving sphincter function whenever possible.
  • A review of 15 non-randomized studies involving 978 patients found that treatments combining botulinum toxin and fissurectomy had an 81% healing rate and low recurrence (6%) and incontinence rates (1%).
  • The results suggest this combination treatment is safe and effective, but more randomized controlled trials are needed to reinforce these findings regarding chronic anal fissures.
View Article and Find Full Text PDF

This study sheds light on the personal characteristics of older Canadians self-identifying as severely anxious and the coping strategies that they gravitated to mitigate their anxiety. Our studied sample consisted of 606 Canadians aged 60 and above who took part in an e-survey across all 10 of Canada's provinces, launched in July 2022, when social distancing was lifted across the country. Participants completed a personal characteristics questionnaire, the Geriatric Anxiety Scale or GAS-10, and a checklist of everyday coping strategies for mitigating anxiety.

View Article and Find Full Text PDF

Many countries are experiencing a post-pandemic surge in hospital utilization along with accelerating population aging. Maximal hospital efficiency is required, with utilization evidence essential for identifying appropriate hospital or broader health system reforms. We offer an investigation of the most recent pre-COVID year (2019-2020) of complete population-based hospital utilization data to describe and compare the use of hospitals by older (65+) and younger (0-64) people admitted for inpatient services in Canada.

View Article and Find Full Text PDF

Ovarian vein syndrome is a rare condition involving the compression of the ureter by the ovarian vein. Since it was first described, very few cases have been reported in literature. We present a case of a 37-year-old female with typical symptoms and common right-side involvement.

View Article and Find Full Text PDF

Background: Type 2 diabetes, cardiovascular disease, and related cardiometabolic disturbances are increasing rapidly in the Asia-Pacific region. We investigated the contribution of excess adiposity, a key determinant of type 2 diabetes and cardiovascular risk, to unfavourable cardiometabolic profiles among Asian ethnic subgroups.

Methods: The Health for Life in Singapore (HELIOS) Study is a population-based cohort comprising multiethnic Asian men and women living in Singapore, aged 30-84 years.

View Article and Find Full Text PDF

There is considerable evidence for mitochondrial-nuclear co-adaptation as a key evolutionary driver. Hypotheses regarding the roles of sex-linkage have emphasized Z-linked nuclear genes with mitochondrial function (N-mt genes), whereas it remains contentious whether the perfect co-inheritance of W genes with mitogenomes could hinder or facilitate co-adaptation. Young (neo-) sex chromosomes that possess relatively many N-mt genes compared to older chromosomes provide unprecedented hypothesis-testing opportunities.

View Article and Find Full Text PDF

Objectives: From a cross-cultural perspective, aging well may encompass pertinent challenges in terms of adjustment, sexual well-being, and satisfaction with life in the late years. Considering the paucity of empirical data concerning cultural diversity of experiencing aging, this study aims to help fill this gap by assessing the specific patterns of sexual satisfaction, adjustment to aging (AtA), and life satisfaction with life (SwL) of older adults in Portugal and Spain.

Methods: This cross-national study included 326 older adults, age 65 and older, from Portugal and Spain.

View Article and Find Full Text PDF

Introduction: Currently, no reporting guidelines exist for observational and qualitative study protocols. In an effort to enhance the quality of research protocols, we introduce two study protocol reporting checklists that we have developed.

Main Recommendations: These checklists include educational components and examples intended to assist novice researchers.

View Article and Find Full Text PDF

Background: Sonothrombolysis is a therapeutic application of ultrasound with ultrasound contrast for patients with ST elevation myocardial infarction (STEMI). Recent trials demonstrated that sonothrombolysis, delivered before and after primary percutaneous coronary intervention (pPCI), increases infarct vessel patency, improves microvascular flow, reduces infarct size, and improves ejection fraction. However, it is unclear whether pre-pPCI sonothrombolysis is essential for therapeutic benefit.

View Article and Find Full Text PDF

Mercury concentrations ([Hg]) in fish reflect a complex array of interacting biogeochemical and ecological variables. In northern regions where fish are a critical subsistence food, understanding and predicting fish [Hg] can be particularly difficult, largely due to a paucity of comprehensive data associated with the logistical challenges of field sampling. Building on previous work where we elucidated causal relationships between fish [Hg] and a variety of catchment, water quality, and ecological variables in subarctic lakes, we investigated whether using only ratios of catchment area to lake area (CA:LA) can predict [Hg] in northern freshwater fish species.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to estimate survival scenarios for patients with ER-positive metastatic breast cancer (MBC) to better communicate prognosis when they start endocrine therapy (ET).
  • - Researchers analyzed data from 25 clinical trials involving over 10,500 patients, finding median overall survival (OS) times of 61.3 months for first-line ET with certain inhibitors, and shorter OS for other treatments.
  • - The findings showed that using simple multiples of the median OS can accurately predict various survival percentiles, helping clinicians guide patients on what to expect from their treatment.
View Article and Find Full Text PDF

Purpose: To evaluate natural language processing (NLP) methods to infer metastatic sites from radiology reports.

Methods: A set of 4,522 computed tomography (CT) reports of 550 patients with 14 types of cancer was used to fine-tune four clinical large language models (LLMs) for multilabel classification of metastatic sites. We also developed an NLP information extraction (IE) system (on the basis of named entity recognition, assertion status detection, and relation extraction) for comparison.

View Article and Find Full Text PDF

Vascular compression syndromes are a diverse group of pathologies that can manifest asymptomatically and incidentally in otherwise healthy individuals or symptomatically with a spectrum of presentations. Due to their relative rarity, these syndromes are often poorly understood and overlooked. Early identification of these syndromes can have a significant impact on subsequent clinical management.

View Article and Find Full Text PDF
Article Synopsis
  • Retrocaval ureter is a rare condition where the ureter (a tube that carries urine) is located abnormally behind a blood vessel.
  • In this report, doctors studied a 38-year-old man with this condition and looked at images from ultrasound and other scans to see how it looks.
  • This case helps show what a retrocaval ureter looks like on different types of medical images, adding to the knowledge about this unusual issue.
View Article and Find Full Text PDF
Article Synopsis
  • Colon cancer outcomes have improved in the U.S. over the past thirty years, but disparities remain, particularly in rural areas, where distance to treatment facilities may impact diagnosis and mortality rates.
  • An analysis of data from the National Cancer Database showed that over 356,000 adult colon cancer patients experienced more advanced disease stages and longer wait times for surgery as their distance from treatment centers increased.
  • The study concluded that living further from treatment facilities is associated with higher mortality rates and highlights the need for targeted interventions to improve cancer care access in rural populations.
View Article and Find Full Text PDF

Aim: To analyse key pregnancy and birth outcomes for First Nations women and children at a Western Sydney metropolitan tertiary referral centre.

Methods: The birth and health-determining characteristics of 470 First Nations infants born at Nepean Hospital in 2018 and their mothers were included in a retrospective audit and compared with a contemporaneous control group of 470 infants and their mothers.

Results: Mothers of First Nations infants had significantly higher rates of socioeconomic disadvantage (P < 0.

View Article and Find Full Text PDF

Purpose: Accurate staging of ovarian cancer is critical to guide optimal management pathways. North American guidelines recommend contrast-enhanced CT as the primary work-up for staging ovarian cancer. This meta-analysis aims to compare the diagnostic accuracy of contrast-enhanced CT alone to PET/CT for detecting abdominal metastases in patients with a new or suspected diagnosis of ovarian cancer.

View Article and Find Full Text PDF

Background: Nutrition and exercise are the mainstay of therapy for the prevention and treatment of frailty in cirrhosis. This pilot study assessed feasibility of the online delivery of an app-based semi-supervised nutrition and exercise intervention in this population.

Methods: The 11-week pilot recruited adults with cirrhosis who owned internet-connected devices.

View Article and Find Full Text PDF