Publications by authors named "Love Gupta"
Rising cases of type 2 diabetes (T2D) in India, especially in metropolitan cities is an increasing concern. The individuals that were most affected are young professionals working in the corporate sector. However, the corporate sector has remained the least explored for T2D risk predisposition.
View Article and Find Full Text PDFBackground: Varicose vein is a chronic condition that affects the lower extremities of the human body. Several factors have been implicated in the development of this disease, viz age, gender, weight, height and prolonged standing. Recently, genome-wide studies have identified genetic biomarkers that are associated with varicose veins in different ethnic groups.
View Article and Find Full Text PDFArticle Synopsis
- Clopidogrel is commonly used to prevent heart-related issues in patients with coronary artery disease, but its effectiveness can vary due to genetic differences in the CYP2C19 gene, especially among South Asians who are at higher cardiac risk.
- A study involving 1191 South Asian Indian individuals revealed a genetic link between CYP2C19 variants and acute coronary syndrome (ACS), highlighting that people with certain polymorphisms, like the *2 allele, are at increased risk, while the *17 allele may offer protective benefits.
- Understanding these genetic influences is crucial for optimizing clopidogrel therapy and improving treatment outcomes for patients in this population.