A portable hydrogel kit based on Au@GM88A/I combined with mobile phone for polychromatic semi-quantitative and quantitative sensing analysis.

The development of an affordable, portable, and instrument-free colorimetric biosensor holds significant importance for routine monitoring and clinical diagnosis. To overcome the limitations that traditional monochromatic colorimetric kits struggle to distinguish subtle color changes with the naked eye, we designed and constructed a portable hydrogel kit for polychromatic semi-quantitative and quantitative sensing analysis. When the actual samples and I- were introduced into a gelatin hydrogel encapsulated with MIL-88A(Fe), Au NRs and oxidase (Au@GM88A/I), a noticeable color change occurred.

Emerging innovations in portable chemical sensing devices: Advancements from microneedles to hydrogel, microfluidic, and paper-based platforms.

With the public heightened emphasis on mitigating the occurrence risks of health-related ailment and optimizing personal physical performance, portable chemical sensing devices emerged as an indispensable component of pervasive health monitoring. Chemical sensing enabled the immediate and on-site identification of biomarkers in biological fluids by integrating colorimetry, fluorescence, electrochemical, and other methods into portable sensor devices. These sensor devices incorporated microneedles, hydrogels, microfluidic modules, and papers, facilitating conformal human-device contact and providing several visual sensing options for disease prevention and healthcare management.

Polydopamine on Copper-Doped Cerium Dioxide Nanosheets as Peroxidase Mimics for the Intelligent Detection of Cholesterol.

The catalytic ability of nanozymes has become an enzymology hotspot in the field of application. Most nanozymes were characterized to simultaneously have oxidase-like and peroxidase-like activities, but the practical application often focuses on certain activity; other complex activities may cause interference. The peroxidase-like activity (POD-like activity) of nanozymes have been widely used in the colorimetric detection of HO or substances producing HO as an intermediate, such as the detection of small biological molecules with the oxidative reaction of a chromogenic reagent in the presence of POD-like nanozymes.