Publications by authors named "Louise Svenstrup"
Article Synopsis
- - The study investigates whether splitting human chorionic gonadotrophin (HCG) support in IVF cycles enhances progesterone levels compared to traditional methods.
- - Conducted at a fertility clinic in Denmark, 69 patients were randomized into three groups, with different HCG dosage and timing strategies for ovulation trigger.
- - Results indicated that patients receiving sequential HCG support (Group 3) had significantly higher progesterone levels post-ovulation retrieval, although four participants experienced ovarian hyperstimulation syndrome.
Research Question: Is there an association between the ovulation trigger dose of human chorionic gonadotrophin (HCG) and endogenous progesterone production during the luteal phase?
Design: This randomized controlled four-arm study, at the Fertility Clinic, Odense University Hospital, Denmark, included women undergoing gonadotrophin-releasing hormone (GnRH) antagonist IVF treatment with ≤11 follicles ≥12 mm. Group 1-3 were triggered with 5000 IU, 6500 IU or 10,000 IU HCG, respectively, receiving 17α-hydroxyprogesterone caproate intramuscularly for luteal-phase support (LPS) to measure endogenous progesterone production. Group 4 received 6500 IU HCG trigger and vaginal progesterone.
Research Question: Should intrauterine insemination be carried out before or after follicle rupture, and is there a difference in sex ratio, according to follicle rupture at the time of insemination?
Design: In this retrospective cohort study conducted at the Fertility Clinic, Odense University Hospital, Denmark, data from 6701 homologous insemination cycles were analysed. Follicle rupture was determined by transvaginal ultrasonography at the time of insemination. The pregnancy rate, clinical pregnancy rate (CPR) and live birth rate (LBR) were recorded.