Signal drift in diffusion MRI of the brain: effects on intravoxel incoherent motion parameter estimates.

Objectives: Signal drift has been put forward as one of the fundamental confounding factors in diffusion MRI (dMRI) of the brain. This study characterizes signal drift in dMRI of the brain, evaluates correction methods, and exemplifies its impact on parameter estimation for three intravoxel incoherent motion (IVIM) protocols.

Materials And Methods: dMRI of the brain was acquired in ten healthy subjects using protocols designed to enable retrospective characterization and correction of signal drift.

Detailed MRI evaluation of the spine: a 2-year follow-up study of young individuals reporting different training doses.

Objective: To characterize the discs and vertebrae in detail over time in a group of adolescent individuals with varying training doses using magnetic resonance imaging (MRI).

Method: Thirty-five students were recruited from regular high schools (n=13) as well as schools with athlete competitive skiing programmes (n = 22). The thoraco-lumbar spine of all individuals was examined at baseline and at 2-year follow-up using the same 1.