Mentimeter Improves Student Engagement in Online Clinical Anatomy Revision Sessions: A Programme Evaluation.

Background There is a need to develop evidence-based strategies to maximise student engagement in online learning contexts. Audience response systems (ARS) are well-established active learning tools that improve engagement in the face-to-face classroom, but they remain under-researched in the online context. Aims This study aimed to directly compare student engagement, perceptions and learning following clinical anatomy revision sessions including interactive questions asked using an ARS (Mentimeter) compared to interactive questions asked using videoconferencing interaction only.

Alzheimer's disease-associated P460L variant of EphA1 dysregulates receptor activity and blood-brain barrier function.

Introduction: Genome-wide association studies link susceptibility to late-onset Alzheimer's disease (LOAD) with EphA1. Sequencing identified a non-synonymous substitution P460L as a LOAD risk variant. Other Ephs regulate vascular permeability and immune cell recruitment.

Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT.

Background: Data are limited regarding the optimal dose and duration of amoxicillin treatment for community-acquired pneumonia in children.

Objectives: To determine the efficacy, safety and impact on antimicrobial resistance of shorter (3-day) and longer (7-day) treatment with amoxicillin at both a lower and a higher dose at hospital discharge in children with uncomplicated community-acquired pneumonia.

Design: A multicentre randomised double-blind 2 × 2 factorial non-inferiority trial in secondary care in the UK and Ireland.

Endothelial cell damage in heparin-induced thrombocytopenia.

Heparin-induced thrombocytopenia type II is a severe complication of heparin treatment that may result in thrombosis. When thrombosis occurs it carries a 50% mortality rate. The exact pathophysiology is not fully understood but in the majority of cases it is associated with the production of heparin/platelet factor 4 antibodies.

A re-appraisal of the reliability of the 20 m multi-stage shuttle run test.

Most studies that have set out to quantify the test-retest reliability of the multi-stage shuttle run test (MSSRT) have typically used inappropriate statistics (correlation coefficients) and/or one of two possible calculation methods for deriving predictions of maximal oxygen uptake (VO2max), and have not considered the impact of habituation on performance in the MSSRT and whether its reliability improves beyond a single repeat trial. In this context, the aim of this study was to assess the reliability of the MSSRT over three trials. Thirty-five healthy and active university games players (22 males and 13 females) performed the MSSRT on three occasions, 1 week apart.