Publications by authors named "Louise Oppermann"
J Immunol Res
December 2023
Article Synopsis
- Amphiregulin (AREG) is a key ligand for the epidermal growth factor receptor (EGFR) that affects monocyte-induced cell death and T-cell responses in peripheral blood.
- The study found that AREG reduces T-cell proliferation during stimulation and down-regulates costimulatory molecules on monocytes, indicating its role in modulating immune responses.
- Additionally, AREG influences T-cell polarization, leading to an increase in IL-17-producing T cells, while maintaining the regulatory T cell proportion.
