Publications by authors named "Louise Bowler"

Article Synopsis
  • Chaste is an open-source simulation package designed for solving mathematical models related to physiology and biology, focusing on areas such as cardiac electrophysiology, soft tissue modeling, and lung ventilation.
  • Cardiac Chaste offers a high-performance, verified simulation tool for accurate heart modeling, while Cell-based Chaste provides extensible frameworks for simulating biological tissues through various cellular models.
  • Lung Chaste presents a novel software package that integrates detailed airway mechanics with overall lung ventilation, making it available for researchers and enhancing understanding of tissue growth and repair in biology.
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Distinct electrophysiological phenotypes are exhibited by biological cells that have differentiated into particular cell types. The usual approach when simulating the cardiac electrophysiology of tissue that includes different cell types is to model the different cell types as occupying spatially distinct yet coupled regions. Instead, we model the electrophysiology of well-mixed cells by using homogenisation to derive an extension to the commonly used monodomain or bidomain equations.

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