Synopsis of recent research by authors named "Louis Panzica"
Louis Panzica's research primarily focuses on understanding cellular behaviors in complex disease environments, including the mechanisms of tumor cell dormancy in breast cancer and the immune dysfunction associated with chronic obstructive pulmonary disease (COPD).
In his study on breast cancer, Panzica utilized a 3D bone niche model to identify specific genes that regulate the dormancy of tumor cells, revealing a p38-MAPK-dependent mechanism in triple-negative breast cancer cells.
His work on COPD highlights the role of chronic inflammation and the influence of cigarette smoke on the immune response within the lung microenvironment, emphasizing the complexity of immune dysfunction in this disease.
