Publications by authors named "Louis N Sorkin"

Article Synopsis
  • Researchers managed to extract the mitochondrial genome (mitogenome) of bed bugs from high-throughput sequencing data that was initially aimed at studying their nuclear genome.
  • The assembled mitogenome shows a characteristic bias toward AT nucleotide composition, which is common among various insect species.
  • Phylogenetic analysis of protein-coding genes reveals that bed bugs belong to a paraphyletic group within the Cimicomorpha clade of the Hemiptera order.
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The common bed bug (Cimex lectularius) has been a persistent pest of humans for thousands of years, yet the genetic basis of the bed bug's basic biology and adaptation to dense human environments is largely unknown. Here we report the assembly, annotation and phylogenetic mapping of the 697.9-Mb Cimex lectularius genome, with an N50 of 971 kb, using both long and short read technologies.

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Although wolf spider venom has been implicated in necrotic arachnidism without acceptably documented verification, limited, prospectively collected data demonstrate a lack of cutaneous necrosis. The infrequent nature of exposure and inherent difficulty in confirming wolf spider bites in humans makes it challenging to study such envenomations. We present the case of a 20 year-old man with confirmed exposure to the wolf spider who developed cutaneous erythema with ulceration following the bite.

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