Publications by authors named "Louis Mine"
Sickle SCAN™ is a rapid, qualitative, point-of-care lateral flow immunoassay for the identification of AS, AC, SS/Sβthal, SC and CC/Cβthal phenotype. We evaluated this test under the conditions encountered in the French newborn screening (NBS) program for sickle cell disease: a total of 104 dried blood spots (DBSs) were tested with an HPLC reference method and then with the Sickle SCAN™ device. Sickle SCAN™ identified the hemoglobin (Hb) phenotype correctly on 96% of cases.
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- * The study compared PCT measurements from the AQT90 FLEX® with the reference method, finding a strong correlation and minimal bias that doesn't affect clinical decisions.
- * The test shows that PCT remains stable at room temperature for 24 hours in both heparinized macrotubes and EDTA microtubes, allowing for effective testing without prior sample treatment.
Pneumatic tube delivery system (PTS) enables to reduce considerably turnaround times. The aim of the study was to assess the influence of the PTS on the quality of routine biochemical and hematological tests in our laboratory. Blood samples from 6 hospitalized patients and 8 healthy volunteers were analyzed.
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- The study aimed to compare how amoxicillin and ampicillin affect the oxidative metabolism of polymorphonuclear neutrophils (PMNs).
- It involved measuring superoxide radical production in PMNs when exposed to different antibiotic concentrations, with or without external stimulants.
- The results indicated that amoxicillin increased superoxide production without stimulation, while ampicillin did not, suggesting amoxicillin enhances its antibacterial effects but may also lead to side effects like severe rashes.