Publications by authors named "Louis Lhuillier"

Background: A comprehensive analysis of routinely collected pre/perioperative demographic/clinical factors that could predict final visual acuity after primary Descemet membrane endothelial keratoplasty (DMEK) has not been conducted previously.

Methods: A retrospective monocenter cohort study was performed with consecutive patients with Fuchs endothelial corneal dystrophy (FECD) who underwent DMEK or triple-DMEK (DMEK combined with cataract surgery) in 2016-2020 in a French tertiary-care hospital. DMEK-only patients were pseudophakic.

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Article Synopsis
  • A study investigated the safety and effectiveness of transepithelial photorefractive keratectomy (TransPRK) for high myopia, specifically using the ASLA-SCHWIND laser system without the typical use of mitomycin-C to prevent corneal haze.
  • Results from 69 eyes showed a significant improvement in uncorrected and best spectacle-corrected visual acuity after surgery, with high efficacy (95.7%) and safety rates (95.7%), and minimal haze complications (none at grades 3-4).
  • The findings suggest that performing TransPRK without mitomycin-C may be a viable option for treating high myopia, demonstrating good visual outcomes and predictability.
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Purpose: Subluxation techniques are superior to divide-and-conquer in procedure duration, pain, and ultrasound quantity, but their safety in endothelial cell loss (ECL) is unclear. This randomized single-blind noninferiority clinical trial aimed to determine whether subluxation supracapsular phacoemulsification techniques are inferior to a reference endocapsular technique (divide-and-conquer) regarding postoperative corneal ECL.

Methods: Patients (aged18 years or older) with greater than +0.

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Purpose: It remains unclear whether preoperative central graft thickness (CGT) contributes to visual outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK). This retrospective cohort study examined the ability of preoperative and postoperative CGT to predict 12-month best spectacle-corrected visual acuity (BSCVA) after DSAEK for Fuchs endothelial corneal dystrophy/moderate pseudophakic bullous keratopathy/second graft.

Methods: All consecutive patients who underwent DSAEK in 2015 to 2018 were included.

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Purpose: To describe the evolution of best spectacle-corrected visual acuity (BSCVA) after Descemet stripping automated endothelial keratoplasty (DSAEK) for very advanced pseudophakic bullous keratopathy (PBK) and to determine whether the thickness of corneal grafts in DSAEK surgery for advanced PBK correlates with BSCVA 6 months postoperatively.

Methods: In a prospective, single-center, observational study, 141 eyes treated with DSAEK surgery were studied, from patients requiring posterior lamellar transplantation for advanced PBK. Graft thickness was measured during the surgery and in vivo 6 months later.

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Purpose: To study the correlation between postoperative corneal edema and endothelial cell loss after cataract surgery by microcoaxial phacoemulsification.

Methods: Eighty-five eyes of 85 consecutive patients with mild cataract (up to C5, N4, and P5: per LOCS III classification) were included in a prospective study from September 2014 to November 2014. Eighty-five eyes were necessary to obtain a precision of 0.

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Purpose: To evaluate and compare visibility and depth of the stromal demarcation line (DL) created after corneal collagen cross-linking (CXL) using anterior segment optical coherence tomography (AS-OCT) between 2 groups: CXL with isoosmolar and hypoosmolar riboflavin.

Methods: In this retrospective study performed at Metz-Thionville Regional Hospital, consecutive patients with progressive keratoconus underwent CXL using an accelerated protocol (10 min, 9 mW/cm ultraviolet-A). AS-OCT (RS-3000, Nidek) was performed at 1 month after surgery, with stromal DL visibility graded.

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Objective: To assess objective and subjective visual outcomes achieved by patients with corneal endothelial dysfunction who have undergone surgical treatment with Descemet stripping automated endothelial keratoplasty (DSAEK).

Methods: A total of 40 eyes of 36 patients with corneal endothelial dysfunction underwent DSAEK. All were followed up for 1 year.

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Purpose: To assess the impact of surgeon experience on early postoperative central corneal thickness (CCT) in eyes that have undergone phacoemulsification-based cataract surgery.

Methods: One hundred sixty eyes underwent phacoemulsification-based cataract surgery performed by an experienced surgeon (n = 110; senior group) or a surgically less experienced ophthalmic assistant (n = 50; junior group), using the divide-and-conquer or tilt-and-tumble technique for cataractous lens extraction. The primary endpoint was postoperative corneal edema 2 hours after surgery, determined by pachymetry-based CCT.

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