Publications by authors named "Louis Joseph Bour"
BMC Med Res Methodol
August 2021
Article Synopsis
- Randomization is crucial in clinical trials as it reduces selection bias, ensures balanced treatment groups, and enhances the validity of statistical tests; the paper discusses various restricted randomization methods for improving these processes.
- The authors evaluate multiple restricted randomization procedures, analyzing their statistical properties such as balance and error rates, and comparing their effectiveness through simulations and real-life examples.
- The findings highlight that different procedures have varying strengths, especially when assumptions are violated, and emphasize the importance of covariate-adjusted analysis and careful selection of randomization methods, especially with small sample sizes.
