Synthesis of O-labelled alcohols from unlabelled alcohols.

The synthesis of primary, secondary and tertiary 18O-enriched alcohols from readily available 16O-alcohols via a Mitsunobu esterification and hydrolysis is described. The method is further exemplified in the labelling of the active pharmaceutical ingredient, dropropizine and is shown to be tolerant of modern, separation friendly Mitsunobu reagents.

On observing acoustic backscattering from salinity turbulence.

It has been hypothesized that at sufficiently high levels of oceanic salinity turbulence it should be possible to observe acoustic backscattering. However, there have been limited in situ measurements to confirm this hypothesis. Using an autonomous underwater vehicle equipped with upward and downward looking 1.

Acoustic scattering from a thermally driven buoyant plume revisited.

Far-field weak scattering theory is applied to the case of high-frequency broad-bandwidth acoustic scattering from a thermally generated buoyant plume in a controlled laboratory environment. To first order, the dominant scattering mechanism is thermally driven sound-speed variations that are related to temperature deviations from ambient. As a result, the received complex acoustic scattering is a measure of the one-component three-dimensional Fourier transform of the temperature difference field measured at the Bragg wave number.