Monitoring Guideline Adherence in Severe Traumatic Brain Injury.

Traumatic brain injuries (TBI) significantly impact global health, often resulting in death or long-term disability. We developed a quality dashboard to monitor adherence to severe TBI guidelines, leveraging data from Rennes University Hospital's clinical data warehouse collected between January 2020 and December 2023. We included 193 patients from the surgical ICU who were over 18 years old and excluded those without adequate intracranial pressure (ICP) monitoring data.

A landscape of germ line mutations in a cohort of inherited bone marrow failure patients.

Bone marrow (BM) failure (BMF) in children and young adults is often suspected to be inherited, but in many cases diagnosis remains uncertain. We studied a cohort of 179 patients (from 173 families) with BMF of suspected inherited origin but unresolved diagnosis after medical evaluation and Fanconi anemia exclusion. All patients had cytopenias, and 12.