Fractional and stochastic modeling of breast cancer progression with real data validation.

This study presents a novel approach to modeling breast cancer dynamics, one of the most significant health threats to women worldwide. Utilizing a piecewise mathematical framework, we incorporate both deterministic and stochastic elements of cancer progression. The model is divided into three distinct phases: (1) initial growth, characterized by a constant-order Caputo proportional operator (CPC), (2) intermediate growth, modeled by a variable-order CPC, and (3) advanced stages, capturing stochastic fluctuations in cancer cell populations using a stochastic operator.

Analysis of octane isomer properties via topological descriptors of line graphs.

Currently, graph-based molecular structure descriptors are frequently used in QSAR (Quantitative Structure-Activity Relationship) and QSPR (Quantitative Structure-Property Relationship) modeling of the properties of chemical compounds. Octane isomers have an important role in the testing of such relationships. In this study, we compute some well-known topological descriptors of the molecular graphs of isomeric octanes and their line graphs, both indices and coindices.

Analysis of Entropy Generation via Non-Similar Numerical Approach for Magnetohydrodynamics Casson Fluid Flow with Joule Heating.

This analysis emphasizes the significance of radiation and chemical reaction effects on the boundary layer flow (BLF) of Casson liquid over a linearly elongating surface, as well as the properties of momentum, entropy production, species, and thermal dispersion. The mass diffusion coefficient and temperature-dependent models of thermal conductivity and species are used to provide thermal transportation. Nonlinear partial differential equations (NPDEs) that go against the conservation laws of mass, momentum, heat, and species transportation are the form arising problems take on.

Optimizing control efficiency in discrete-time multi-agent systems via event-triggered containment techniques combining disturbance handling and input delay management.

The goal of this paper is to mitigate disturbances and input delays while optimizing controller actuation updates for discrete-time multi-agent systems through the use of an event-triggered confinement control system, especially in resource-constrained scenarios. This approach when combined with event-triggered control techniques, then every follower in the system adjusts its condition at specified times based on an event-triggered condition that is suggested. The containment control system issue in the presence of disturbances and input delays was tackled by using both decentralized and centralized event-triggered control systems.

Embedding channel pruning within the CNN architecture design using a bi-level evolutionary approach.

Remarkable advancements have been achieved in machine learning and computer vision through the utilization of deep neural networks. Among the most advantageous of these networks is the convolutional neural network (CNN). It has been used in pattern recognition, medical diagnosis, and signal processing, among other things.

Topology optimization search of deep convolution neural networks for CT and X-ray image classification.

Covid-19 is a disease that can lead to pneumonia, respiratory syndrome, septic shock, multiple organ failure, and death. This pandemic is viewed as a critical component of the fight against an enormous threat to the human population. Deep convolutional neural networks have recently proved their ability to perform well in classification and dimension reduction tasks.

Joint design and compression of convolutional neural networks as a Bi-level optimization problem.

Over the last decade, deep neural networks have shown great success in the fields of machine learning and computer vision. Currently, the CNN (convolutional neural network) is one of the most successful networks, having been applied in a wide variety of application domains, including pattern recognition, medical diagnosis and signal processing. Despite CNNs' impressive performance, their architectural design remains a significant challenge for researchers and practitioners.

Hemolysis contributes to anemia during long-duration space flight.

Anemia in astronauts has been noted since the first space missions, but the mechanisms contributing to anemia in space flight have remained unclear. Here, we show that space flight is associated with persistently increased levels of products of hemoglobin degradation, carbon monoxide in alveolar air and iron in serum, in 14 astronauts throughout their 6-month missions onboard the International Space Station. One year after landing, erythrocytic effects persisted, including increased levels of hemolysis, reticulocytosis and hemoglobin.

Two simple modifications can potentially change the future of proximal hypospadias surgery. Our series and a review of the literature.

Background/objective: To draw a hint towards two simple modifications that could potentially decrease the complication rate.

Patients And Methods: It was a single center, single operator and retrospective study. All patients with severe hypospadias operated according to koyanagi with or without modifications were presented.

Quantitative analysis of repaired rabbit supraspinatus tendons (± channeling) using magnetic resonance imaging at 7 Tesla.

Background: The quantitative assessment of supraspinatus tendons by conventional magnetic resonance is limited by low contrast-to-noise ratio (CNR). Magnetic resonance imaging (MRI) scanners operating at 7 Tesla offer high signal-to noise ratio (SNR), low CNR and high spatial resolution that are well-suited for rapidly relaxing tissues like tendons. Few studies have applied T2 and T2* mapping to musculoskeletal imaging and to the rotator cuff tendons.

Rotator cuff anchor repair: Histological changes associated with the recovering mechanical properties in a rabbit model.

Rotator cuff anchor repair is an increasingly common surgical procedure but the failure rate remains high. In order to improve surgical outcomes, a better understanding of postrepair histological and cellular responses at the tendon-bone attachment site (enthesis) is needed. We examined operated shoulders from 42 New Zealand female white rabbits.

Six degrees head-down tilt bed rest caused low-grade hemolysis: a prospective randomized clinical trial.

This study aimed to measure hemolysis before, during and after 60 days of the ground-based spaceflight analog bed rest and the effect of a nutritional intervention through a prospective randomized clinical trial. Twenty male participants were hospitalized for 88 days comprised of 14 days of ambulatory baseline, 60 days of 6° head-down tilt bed rest and 14 days of reambulation. Ten participants each received a control diet or daily polyphenol associated with omega-3, vitamin E, and selenium supplements.

Supraspinatus tendon transosseous vs anchor repair surgery: a comparative study of mechanical recovery in the rabbit.

Background: Supraspinatus (SSP) tendon ruptures requiring surgical repair are common. Arthroscopic suture anchor fixation has gradually replaced transosseous repair in supraspinatus tendon tear. Our objective was to compare mechanical properties between transosseous and anchor supraspinatus repair in the first 6 postoperative weeks in a rabbit model.

Determination of Total Hydrocarbons in Contaminated Soil with "Thin Layer Sorptive Extraction Coupled with Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy".

Soil analysis using infrared spectroscopy has been proposed as an alternative to conventional soil analysis to detect soil contamination. This study therefore aims to develop an innovative, , rapid, precise, and inexpensive method that is easy to implement in order to assess soil contamination with hydrocarbons. This work describes the development and validation of a new extraction method by thin-layer sorptive extraction and attenuated total reflectance-Fourier transform infrared spectroscopy (TLSE-ATR-FTIR).

Glenoid exposure in shoulder arthroplasty: the role of soft tissue releases.

Background: The deltopectoral approach is commonly used in shoulder arthroplasty. Various soft tissue releases can be performed to obtain adequate glenoid exposure, but their effectiveness is not known. The purpose of this study was to (1) quantify the effects of various releases on the amount of glenoid surface area exposure and (2) determine if common soft tissue releases performed about the shoulder significantly improve exposure of the glenoid.

Measuring Human Hemolysis Clinically and in Extreme Environments Using Endogenous Carbon Monoxide Elimination.

The measure of hemolysis in humans is clinically important. Here we describe methods using a gas chromatograph equipped with a reduction gas detector to detect the human analyte carbon monoxide (CO) that were developed for the extreme environment of the International Space Station. These methods can be adapted to in-hospital use for clinical care with characteristics that may surpass existing measures of hemolysis.

Lateral Trochlear Ridge: A Non-Articulating Zone for Anterior-to-Posterior Screw Placement in Fractures Involving the Capitellum and Trochlea.

Background: Coronal shear fractures of the distal aspect of the humerus that involve the capitellum and the trochlea are rare; nevertheless, they are difficult to treat because of the complex fracture patterns and osteochondral nature of the fragments, limiting optimal screw placement. The use of anterior-to-posterior screw fixation by a lag technique (without countersinking) could potentially improve the strength of the construct. Our primary research question was to anatomically determine if there is a non-articulating zone for screw placement along the anterior aspect of the lateral trochlear ridge (aLTR) throughout normal elbow range of motion.

Early femoral component migration: comparing the anterior and posterior approach to the hip.

Purpose: Early femoral component migration is a useful indicator for identifying implants at risk of failure due to aseptic loosening. The goal of this retrospective study was to identify if anterior approach (AA) treated hips are at a higher risk of failure due to aseptic loosening caused by early migration compared to hips operated on using the traditional posterior approach (PA).

Methods: A total of 388 hips were included in this study, 139 AA and 249 PA treated hips.

Comparing In Vivo Performance of Two Highly Cross-Linked Polyethylene Thermal Treatments: Remelting vs Annealing in Acetabular Liners.

Background: The introduction of highly cross-linked polyethylene (HXLPE) acetabular liners has greatly improved the wear performance of metal-on-PE bearing surfaces used in total hip arthroplasty. Changing the sterilization environment and adding thermal treatments, such as remelting or annealing, were introduced to limit on-shelf and in vivo oxidation of cross-linked liners. This study compares the wear properties of the remelted A-CLASS (MicroPort) HXLPE liner to a sequentially annealed HXLPE.

Posterior malleolus exposure.

Objectives: Posterior malleolus (PM) fractures are common in rotational ankle injuries, tibial plafond fractures, and distal third tibia fractures. Surgical indications continue to evolve as we improve our understanding of ankle and syndesmotic stability. These fractures remain technically challenging with respect to both exposure and fixation.

Self extrusion on an ingested foreign body: a case report.

Foreign body ingestion is a frequent issue in paediatrician's practice. Foreign bodies often pass the gastro-intestinal tract spontaneously but can sometimes generate complications (1% of the cases). The migration of ingested foreign bodies is rare, but their spontaneous extrusion through the skin is even rarer and was previously described only in the neck.

Rare retro peritoneal tumor in infants.

Lipoblastoma is a rare mesenchymal tumor, occuring in less than three-year-old infants in 90% of the cases and in 40% of the cases in chidren aged less than one year. It can be present at birth. It is a benign tumor, with defined margins, that can be locally aggressive, without metastases.

Fixation of Anteromedial Coronoid Facet Fractures: A Biomechanical Evaluation of Plated Versus Screw Constructs.

Objective: To examine the stability of plate (locking and non-) versus screw constructs in the fixation of these fractures.

Methods: An anteromedial coronoid facet fracture (OTA/AO type 21-B1, O'Driscoll type 2, subtype 3) was simulated in 24 synthetic ulna bones that were then assigned to 3 fracture fixation groups: non-locking plate, locking plate (LP), or screw fixation. Each construct was first cycled in tension (through a simulated medial collateral ligament) and then in compression.

Intestinal duplication revealed by posterior reversible encephalopathy syndrome.

We report a unique case of intestinal duplication detected on posterior reversible encephalopathy syndrome (PRES) in a 13-year-old girl. She was admitted to the pediatric Emergency Department because of generalized seizures. Radiological assessment revealed a large, well-defined, thick-walled cystic lesion in the mid abdomen, suggestive of duplication cyst associated to a PRES.