Publications by authors named "Lotte Delemarre"
Article Synopsis
- This study investigates how human serum albumin (HSA) levels affect drug distribution in neonates, aiming to establish trends in HSA over time and create a predictive model for HSA concentrations.
- A total of 848 neonates were analyzed, revealing that HSA concentrations increase with postnatal age and gestational age, and several factors like birth weight and bilirubin levels significantly influence these concentrations.
- The resulting prediction model demonstrated a high performance with an accuracy of 76.3%, providing valuable HSA centiles and insights that could improve clinical care and pharmacotherapy for neonatal patients.
