Using QCM-D to study the adhesion of human gingival fibroblasts on implant surfaces.

Sealing the soft tissue-implant interface is one of the key issues in preventing transcutaneous implant-associated infections. A promising surface modification for improving osseointegration and possibly soft tissue integration is to coat the implant surface with hydroxyapatite (HA) nanoparticles. When new implant materials are developed, their ability to facilitate cell attachment and spreading are commonly investigated in vitro to establish their potential for good in vivo performance.

Evaluation of bone healing on sandblasted and Acid etched implants coated with nanocrystalline hydroxyapatite: an in vivo study in rabbit femur.

This study aimed at investigating if a coating of hydroxyapatite nanocrystals would enhance bone healing over time in trabecular bone. Sandblasted and acid etched titanium implants with and without a submicron thick coat of hydroxyapatite nanocrystals (nano-HA) were implanted in rabbit femur with healing times of 2, 4, and 9 weeks. Removal torque analyses and histological evaluations were performed.

Spontaneously formed nanostructures on titanium surfaces.

Objectives: The aim was to investigate the evolution of nanostructures on the SLActive surface, as a function of time, storage conditions, material dependence and to identify the step in which the reorganization of the outermost titanium oxide layer into well defined nanostructures takes place.

Material And Methods: Titanium grade 2 discs were surface modified in seven different modes; (1) SLA (sand blasted, large grit, acid etched) protocol. (2) SLActive protocol (SLA stored in 0.

Surface characterization of commercial oral implants on the nanometer level.

Lately, there has been a growing interest in how the presence of nanometer structures on a bone integrated implant surface influences the healing process. Recent in vitro studies have revealed an increased osteoblast response to different nanophase surfaces. Some commercial implant brands claim their implants have nanometer structures.