Publications by authors named "Lorraine Bayliss"
Background: In Canada, the Canadian Institutes of Health Research launched the Strategy for Patient-Oriented Research (SPOR) in 2011. The strategy defines 'patient-oriented research' as a continuum of research that engages patients as partners, focuses on patient priorities, and leads to improved patient outcomes. The overarching term 'patient' is inclusive of individuals with personal experience of a health issue as well as informal caregivers including family and friends.
View Article and Find Full Text PDFIntroduction: Healing time for neuropathic planter foot ulcers (NPFUs) in persons with diabetes may be reduced through use of non-removable fiberglass total contact casting (F-TCC) compared with removable cast walkers (RCWs), although the evidence base is still growing.
Research Design And Methods: We conducted a rapid review and systematically searched for, and critically assessed, randomized controlled trials (RCTs) that compared the efficacy of F-TCC versus RCW, focusing on the time to ulcer healing in adult persons (18+ years) with NPFUs and type 1 or type 2 diabetes. We meta-analysed the mean differences and associated 95% CIs using an inverse variance, random-effects model.
Article Synopsis
- Several Canadian provinces are considering reimbursement policies that would allow doctors to substitute higher-cost innovator biologics with cheaper biosimilars, aiming to save costs and affect a significant number of patients.
- A study focused on Ontario analyzed the impact of these policies, revealing that mandatory biosimilar substitutions could save the government substantial amounts (up to $645.9 million) while impacting thousands of patients over a few years.
- The findings suggest that while these policies could reduce costs dramatically, their effects vary based on the criteria used for substitution, highlighting the importance of careful policymaking to balance savings and patient care.
Background: In the past decade, patient-oriented research (POR) has been at the forefront of healthcare research in Canada because it has the potential to make research more meaningful and relevant to patient needs. Despite this growing emphasis on and expectation to conduct POR, there is limited guidance about how to apply POR in practice. To address this capacity building need, the Knowledge Translation (KT) Program and patient partners co-designed, delivered, and evaluated Partners in Research (PiR), a 2-month online course for patients and researchers to collectively learn how to conduct and engage in POR.
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