Publications by authors named "Lorinne Levitt"

Article Synopsis
  • Congenital cytomegalovirus (cCMV) is a major cause of neurodevelopmental disabilities in infants, highlighting the need for better prevention strategies.
  • Researchers studied human CMV infection in decidual tissues from women with and without immunity, finding that those with preconception immunity show resistance to the virus and stimulate specific immune cells upon reinfection.
  • The study suggests that enhancing the immune response in decidual tissues could help develop a vaccine for cCMV and improve understanding of immune defenses at the maternal-fetal interface.
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Objectives: Compare two approaches of expectant management in the setting of term premature rupture of membranes (PROM) among women with prior cesarean delivery.

Methods: A retrospective study conducted in a tertiary care center during 2006 to 2017, including primiparous women with singleton pregnancy and a prior low-transverse cesarean delivery who presented with term PROM and requested trial of labor after cesarean (TOLAC). Outcomes were compared between the two campuses at our center: campus A enabled expectant management up to 48 hours following PROM and campus B enabled up to 24 hours after PROM.

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BACKGROUNDCytomegalovirus (CMV) is the most common intrauterine infection, leading to infant brain damage. Prognostic assessment of CMV-infected fetuses has remained an ongoing challenge in prenatal care, in the absence of established prenatal biomarkers of congenital CMV (cCMV) infection severity. We aimed to identify prognostic biomarkers of cCMV-related fetal brain injury.

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Aim: To compare maternal and neonatal outcomes between the 'head first' and 'legs first' delivery methods during a second stage cesarean section.

Methods: We conducted a retrospective study between January 2009 and May 2015 at a large public university tertiary referral center. Included were all women who underwent cesarean delivery with a fully dilated cervix and a fetal head at the level of the ischial spines or below.

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Introduction: Professional bodies have published guidelines defining the length of the second stage of labor and when it is "prolonged", according to parity and epidural anesthesia administration. Recently these guidelines have been extended, aiming to reduce rates of unplanned cesarean deliveries.

Aims: To examine the risk factors and outcomes of a prolonged second stage of labor, in order to understand its causes and implications for mothers and neonates, including the delivery mode.

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Article Synopsis
  • The study investigates the relationship between large head circumference and vacuum extraction failure during deliveries at a tertiary center from January 2010 to June 2015.
  • Analyzing data from 48,007 deliveries, the researchers identified that out of 3,835 attempted vacuum extractions, 215 (5.6%) resulted in failure, with a significant correlation between large head circumference and increased risk of failure (aOR = 2.31).
  • Other contributing factors included being a first-time mother (primiparity), a prolonged second stage of labor, and the baby’s position (occipito-posterior).
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Background. Late pregnancy usage of angiotensin converting enzyme inhibitors (ACE-I) and angiotensin II receptor blockers (ARB) may cause severe oligohydramnios due to fetal renal impairment. Affected neonates will often suffer from fatal, renal, and respiratory failure.

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Objective: Vacuum extraction of a macrosomic fetus is considered a risk factor for shoulder dystocia (SD). We evaluated maternal and fetal outcomes following vacuum extraction of macrosomic infants.

Methods: A retrospective cohort study conducted in two large teaching hospitals.

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Unlabelled: Whether intra- and early post-partum hemorrhage is influenced by ABO blood groups remains unknown. Therefore, we compared women with O to non-O blood groups with regard to maternal post-partum hemorrhage and transfusion need. This retrospective study was conducted in a single tertiary center between 2005 and 2014.

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Introduction: Re-laparotomy following caesarean delivery (CD) is a rare yet serious complication. The aim of this study was to identify risk factors, diagnostic features and outcomes following re-laparotomy.

Materials And Methods: This retrospective cohort study reviewed cases of re-laparotomy following CD performed at Hadassah-Hebrew University Medical Center.

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