Antinociceptive, cardiopulmonary, and sedative effects of five intravenous infusion rates of lidocaine in conscious dogs.

Objective: To observe antinociceptive, cardiopulmonary and sedative effects of five different 12-hour lidocaine infusions in conscious dogs, and measure plasma lidocaine concentrations.

Study Design: Two-part randomized, prospective, blinded, cross-over experimental study.

Animals: Six neutered male, crossbred dogs approximately 1-2 years of age and weighing 29.