Accuracy, repeatability, and interplatform reproducibility of T quantification methods used for DCE-MRI: Results from a multicenter phantom study.

Purpose: To determine the in vitro accuracy, test-retest repeatability, and interplatform reproducibility of T quantification protocols used for dynamic contrast-enhanced MRI at 1.5 and 3 T.

Methods: A T phantom with 14 samples was imaged at eight centers with a common inversion-recovery spin-echo (IR-SE) protocol and a variable flip angle (VFA) protocol using seven flip angles, as well as site-specific protocols (VFA with different flip angles, variable repetition time, proton density, and Look-Locker inversion recovery).