Publications by authors named "Lori Klouvi"
J Am Coll Cardiol
October 2022
Article Synopsis
- Patients with mitochondrial diseases are at a higher risk for heart failure (HF) and serious heart-related events, prompting the creation of prediction models to estimate these risks.
- In a study involving 600 adult patients, over 6.67 years, 4.9% developed HF, and 5.1% experienced arrhythmic major adverse cardiac events (MACE).
- Key predictors for these heart issues included specific genetic variants, heart structure changes, and reduced heart function as indicated by low ejection fractions.*
Neuromuscul Disord
May 2021
Article Synopsis
- A survey conducted by SMA Europe after a new treatment was approved showed how patients feel about their daily lives and access to treatments for spinal muscular atrophy (SMA).
- 1474 people from 26 countries responded, and many said just keeping their condition stable feels like progress, but there were significant gaps in who could get treatments based on their age and how severe their disease is.
- The survey highlighted the need for more options in treatments, especially combination therapies, and showed that working together among all groups is important for developing new SMA treatments.
