Publications by authors named "Lori Fairservice"
Background And Objectives: Cystic fibrosis (CF) screen-positive infants with an inconclusive diagnosis (CFSPID) are infants in whom sweat testing and genetic analysis does not resolve a CF diagnosis. Lack of knowledge about the health outcome of these children who require clinical follow-up challenges effective consultation. Early predictive biomarkers to delineate the CF risk would allow a more targeted approach to these children.
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- Cystic fibrosis (CF) affects various organs, including the pancreas, which can lead to cystic fibrosis-related diabetes (CFRD), impacting survival rates if untreated.
- Researchers built a CFRD prediction model using genetic data from a Canadian study and validated it with data from a French study, highlighting key predictors like sex and certain genetic variants.
- The final model successfully identifies individuals at high risk for CFRD and has led to the creation of a web-based tool that helps doctors monitor and treat patients based on their specific risk levels.