Publications by authors named "Lori Bergstrom"

Article Synopsis
  • The study explores the impact of the Patient Buddy App on healthcare providers' workloads and finds that while many felt well-trained and confident, concerns exist about technical support and connectivity issues.
  • Providers reported a high volume of alerts during the study, mainly concerning Hepatic Encephalopathy symptoms.
  • The findings suggest that while the App shows promise in enhancing patient-provider communication, it’s crucial to balance the benefits with the potential burden on providers to prevent burnout.
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Background: Health information technology (IT) interventions to decrease readmissions for cirrhosis may be limited by patient-associated factors.

Objective: The aim of this study was to determine perspectives regarding adoption versus refusal of health IT interventions among patient-caregiver dyads.

Methods: Inpatients with cirrhosis and their caregivers were approached to participate in a randomized health IT intervention trial requiring daily contact with research teams via the Patient Buddy app.

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Although it is well established that human cytochrome P450 1 family enzymes are induced by cigarette smoking through activation of the Ah receptor, it is not known whether this leads to increased metabolic activation or detoxification of carcinogenic polycyclic aromatic hydrocarbons (PAH), which are present in cigarette smoke and the general environment. We gave oral doses of deuterated phenanthrene ([D10]Phe), a non-carcinogenic surrogate of carcinogenic PAH such as benzo[a]pyrene, to smokers (N = 170, 1 or 10 μg doses) and non-smokers (N = 57, 1 μg dose). Bioactivation products (dihydrodiol and tetraol) and detoxification products (phenols) of [D10]Phe were determined in 6-h urine to obtain a comprehensive metabolic profile.

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