Revisiting the Historic Strontium-90 Ingestion Beagle Study Conducted at the University of California Davis: Opportunity in Archival Materials.

Strontium-90 is a radionuclide found in high concentrations in nuclear reactor waste and nuclear fallout from reactor accidents and atomic bomb explosions. In the 1950s, little was known regarding the health consequences of strontium-90 internalization. To assess the health effects of strontium-90 ingestion in infancy through adolescence, the Atomic Energy Commission and Department of Energy funded large-scale beagle studies at the University of California Davis.

Structure and Measurement Invariance of Ethnic Identity for Native American College Students.

With a specific focus on the Native American population, the current study investigated the structure of ethnic identity, measured by the Multigroup Ethnic Identity Measure, using a bifactor model across Native American ( = 307), Asian ( = 348), and White ( = 549) undergraduate students. We further investigated measurement invariance across ethnic groups that shared the same factor structure. The results indicated that ethnic identity can be modeled by a bifactor structure with a general factor and two group factors, affective pride and exploration, for Native American and Asian respondents but not White respondents.

What free time? A daily study of work recovery and well-being among working students.

Working students face incredible demands on their time and resources, yet little research exists assessing the degree to which they are able to recover from their demands. The current study aimed to determine the extent to which different types of psychological detachment-detachment from work as well as detachment from school-contribute to the well-being of working students, and whether work can serve as an opportunity to recover from school and vice versa. An additional focus of the study was how perceived stress interacts with detachment both from school and from work to impact well-being.

Math Self-Efficacy and STEM Intentions: A Person-Centered Approach.

Research pertaining to STEM interest and persistence continues to be a top priority in the educational research arena. The current study employed a person-centered approach to examine the impact of math self-efficacy and various distal predictors, such as individuals' demographic information, beliefs about math, and social group identification, on STEM interest and intentions. Specifically, we conducted a latent profile analysis (LPA), thereby inferring three homogeneous subgroups of individuals or latent classes from their response patterns on the 18-item sources of math self-efficacy measure.

Bayesian SEM for Specification Search Problems in Testing Factorial Invariance.

Specification search problems refer to two important but under-addressed issues in testing for factorial invariance: how to select proper reference indicators and how to locate specific non-invariant parameters. In this study, we propose a two-step procedure to solve these issues. Step 1 is to identify a proper reference indicator using the Bayesian structural equation modeling approach.

The relationship between sleep and work: A meta-analysis.

Sleep has tremendous importance to organizations because of its relationship with employee performance, safety, health, and attitudes. Moreover, sleep is a malleable behavior that may be improved by individual and organizational changes. Despite the consequential and modifiable nature of sleep, little consensus exists regarding its conceptualization, and how the choice of conceptualization may impact relationships with organizational antecedents and outcomes.

Fatty acid microemulsion for the treatment of neonatal conjunctivitis: quantification, characterisation and evaluation of antimicrobial activity.

Fatty acids (FAs) are used by many organisms as defence mechanism against virulent bacteria. The high safety profile and broad spectrum of activity make them potential alternatives to currently used topical antibiotics for the treatment of eye infections in neonates. The current study utilised a Design of Experiment approach to optimise the quantification of five fatty acids namely; lauric acid, tridecanoic acid, myristoleic acid, palmitoleic acid and α-linolenic acid.

Correia Repeat Enclosed Elements and Non-Coding RNAs in the Neisseria Species.

Neisseria gonorrhoeae is capable of causing gonorrhoea and more complex diseases in the human host. Neisseria meningitidis is a closely related pathogen that shares many of the same genomic features and virulence factors, but causes the life threatening diseases meningococcal meningitis and septicaemia. The importance of non-coding RNAs in gene regulation has become increasingly evident having been demonstrated to be involved in regulons responsible for iron acquisition, antigenic variation, and virulence.

Insight into proteomic investigations of Neisseria meningitidis serogroup C strain L91543 from analysis of its genome sequence.

Here, we describe the draft sequence of a virulent isolate of Neisseria meningitidis strain L91543, belonging to serogroup C. The findings from previous proteomic and metabolomic studies of this strain can now be further interpreted with genomic analysis. Comparative analysis of the genome sequence revealed close similarity and localized synteny with the genome sequence of N.

Promoting retention of nurses: A meta-analytic examination of causes of nurse turnover.

Background: Because the health care field is expected to be the fastest growing job field until 2020, an urgent need to focus on nurse retention exists.

Purpose: The aim of this study was to examine the relationships between predictors of turnover (i.e.

Microarray analysis of the Ler regulon in enteropathogenic and enterohaemorrhagic Escherichia coli strains.

The type III protein secretion system is an important pathogenicity factor of enteropathogenic and enterohaemorrhagic Escherichia coli pathotypes. The genes encoding this apparatus are located on a pathogenicity island (the locus of enterocyte effacement) and are transcriptionally activated by the master regulator Ler. In each pathotype Ler is also known to regulate genes located elsewhere on the chromosome, but the full extent of the Ler regulon is unclear, especially for enteropathogenic E.

Sequence features contributing to chromosomal rearrangements in Neisseria gonorrhoeae.

Through whole genome sequence alignments, breakpoints in chromosomal synteny can be identified and the sequence features associated with these determined. Alignments of the genome sequences of Neisseria gonorrhoeae strain FA1090, N.gonorrhoeae strain NCCP11945, and N.

Safety performance: the mediating role of safety control.

Objective: Occupational stress models suggest that the ability to understand, predict, and control stressful events minimizes their impact. This study examines the applicability of the stress antidote theory to the safety environment. Newly developed measures assess understanding why and how unsafe events occur, predicting the occurrence of unsafe events, and controlling unsafe events, and how these constructs relate to safety performance at work.

Simple sequence repeats in Helicobacter canadensis and their role in phase variable expression and C-terminal sequence switching.

Background: Helicobacter canadensis is an emerging human pathogen and zoonotic agent. The genome of H. canadensis was sequenced previously and determined to contain 29 annotated coding regions associated with homopolymeric tracts.

The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats.

Laribacter hongkongensis is a newly discovered Gram-negative bacillus of the Neisseriaceae family associated with freshwater fish-borne gastroenteritis and traveler's diarrhea. The complete genome sequence of L. hongkongensis HLHK9, recovered from an immunocompetent patient with severe gastroenteritis, consists of a 3,169-kb chromosome with G+C content of 62.

Comparative analysis of two Neisseria gonorrhoeae genome sequences reveals evidence of mobilization of Correia Repeat Enclosed Elements and their role in regulation.

Background: The Correia Repeat Enclosed Element (CREE) of the Neisseria spp., with its inverted repeat and conserved core structure, can generate a promoter sequence at either or both ends, can bind IHF, and can bind RNase III and either be cleaved by it or protected by it. As such, the presence of this element can directly control the expression of adjacent genes.

Bacterial flagellar diversity and evolution: seek simplicity and distrust it?

Flagella are the chief organelles of motility in bacteria. In recent years, several new findings have illuminated the evolution of bacterial flagella, including cut-down versions of the organelle in Buchnera, a dispensable ATPase and structural evidence for homology between FliG (a component of the flagellar motor) and MgtE (a magnesium transporter). However, a fresh examination of the phylogenetic distribution of flagellar genes warns against a simplistic model of early flagellar evolution.

Occupational safety: application of the job demand-control-support model.

The utility of the job demand-control-support (JDCS) model for explaining psychological and physical well-being has been documented in a variety of settings. The current study's purpose was to assess the effectiveness of the JDCS model for predicting occupational safety well-being criteria (i.e.

Sequence-based analysis of pQBR103; a representative of a unique, transfer-proficient mega plasmid resident in the microbial community of sugar beet.

The plasmid pQBR103 was found within Pseudomonas populations colonizing the leaf and root surfaces of sugar beet plants growing at Wytham, Oxfordshire, UK. At 425 kb it is the largest self-transmissible plasmid yet sequenced from the phytosphere. It is known to enhance the competitive fitness of its host, and parts of the plasmid are known to be actively transcribed in the plant environment.

xBASE2: a comprehensive resource for comparative bacterial genomics.

xBASE is a genome database aimed at helping laboratory-based bacteriologists make best use of bacterial genome sequence data, with a particular emphasis on comparative genomics. The latest version, xBASE 2.0 (http://xbase.

The repertoire of minimal mobile elements in the Neisseria species and evidence that these are involved in horizontal gene transfer in other bacteria.

In the Neisseria spp., natural competence for transformation and homologous recombination generate antigenic variants through creation of mosaic genes (such as opas) and through recombination with silent cassettes (such as pilE/pilS) and gene-complement diversity through the horizontal exchange of whole genes or groups of genes, in minimal mobile elements (MMEs). An MME is a region encompassing 2 conserved genes between which different whole-gene cassettes are found in different strains, which are chromosomally incorporated solely through the action of homologous recombination.

The underreporting gap in aggressive incidents from geriatric patients against certified nursing assistants.

Staff in the health care industry experience workplace aggression at a much higher rate than the general workforce. However, a large proportion of aggressive incidents go unreported, and the source of many of these incidents is patients. This study investigates aggressive incidents from patients against certified nursing assistants (CNAs; n = 76) in a sample of six geriatric care facilities.

Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.

The bacterium Neisseria meningitidis is commonly found harmlessly colonising the mucosal surfaces of the human nasopharynx. Occasionally strains can invade host tissues causing septicaemia and meningitis, making the bacterium a major cause of morbidity and mortality in both the developed and developing world. The species is known to be diverse in many ways, as a product of its natural transformability and of a range of recombination and mutation-based systems.

The small FNR regulon of Neisseria gonorrhoeae: comparison with the larger Escherichia coli FNR regulon and interaction with the NarQ-NarP regulon.

Background: Neisseria gonorrhoeae can survive during oxygen starvation by reducing nitrite to nitrous oxide catalysed by the nitrite and nitric oxide reductases, AniA and NorB. The oxygen-sensing transcription factor, FNR, is essential for transcription activation at the aniA promoter, and full activation also requires the two-component regulatory system, NarQ-NarP, and the presence of nitrite. The only other gene known to be activated by the gonococcal FNR is ccp encoding a cytochrome c peroxidase, and no FNR-repressed genes have been reported in the gonococcus.