Cardiovascular morbidity and long term mortality associated with in hospital small increases of serum creatinine.

Background: The cardiovascular risk associated with an increase in serum creatinine below the acute kidney injury (AKI) threshold, during hospitalization, has not been studied in depth. We assessed patients' features and outcomes associated with these changes.

Methods: Retrospective cohort study of 12,493 consecutive patients admitted to hospital throughout 12 months.

Characteristics of the Relationship of Kidney Dysfunction with Cardiovascular Disease in High Risk Patients with Diabetes.

We aimed at comparing the relationship of reduced estimated glomerular filtration rate (eGFR) with cardiovascular disease (CVD) and mortality between high risk patients with and without type 2 diabetes mellitus (T2DM). The cross-sectional study evaluated 16,298 participants (1,627 T2DM) acutely admitted to hospital. The longitudinal study comprised 7,508 patients (673 with diabetes and 6,835 without).

Association of reduced kidney function with cardiovascular disease and mortality in elderly patients: comparison between the new Berlin initiative study (BIS1) and the MDRD study equations.

Background: New creatinine based equations for estimating glomerular proposed for aged subjects have not been assessed in their association of reduced eGFR with cardiovascular (CV) morbidity or all cause (AC) mortality.

Patients: All subjects ≥70 years old (2998) who had been admitted to the hospital during a 12 month period were examined.

Methods: In a cohort study we applied the new Berlin Initiative Study (BIS1) equation.

Thrombotic microangiopathic nephropathy, pulmonary hypertension and nephromegaly: case report of a patient treated with endothelin receptor antagonist.

The coexistence of thrombotic microangiopathic nephropathy and pulmonary hypertension has only been described in association with malignancy and its treatment. Here we describe a 14-year-old boy with no prior medical history who presented with hypertension, proteinuria and nephromegaly, and then developed progressive pulmonary hypertension. Renal histology showed lesions consistent with glomerulopathy due to thrombotic microangiopathy (TMA).

Reduced kidney function and outcome in acute ischaemic stroke: relationship to arterial hypertension and diabetes.

Background: Stroke is a dangerous long-term complication of kidney failure, yet its occurrence early in disease is poorly characterized. Our aim was to investigate the association of reduced kidney function, hypertension and diabetes with acute ischaemic stroke and the outcome thereof.

Methods: In this prospective cohort study, the association of reduced kidney function, hypertension and diabetes with stroke and 2-year all-cause mortality was investigated.

Kidney function and mortality in different cardiovascular diseases: relationship with age, sex, diabetes and hypertension.

Background: The aim of this study was to investigate the association of reduced kidney function, diabetes and arterial hypertension with mortality in cardiovascular disease patients admitted to hospital.

Methods: This was a prospective cohort study. The setting was the reference hospital for the population area.

Resistant arterial hypertension: association with syncronous kidney cancer and adrenal adenoma.

The coexistence of renal cancer and adrenal adenoma is rare. We report the case of a 60-year-old patient with synchronous hypernephroma and adrenal adenoma. The patient presented with resistant hypertension, high plasma renin activity and aldosterone and target organ damage.

Validation of the A&D UA-705 device for self-measurement of blood pressure according to the British Hypertension Society protocol.

Objectives: We tested the accuracy of the UA-705 blood pressure semi-automatic monitor.

Methods: Device evaluation was performed according to the modified British Hypertension Society protocol released in 1993. Eighty-five patients with characteristics outlined in the British Hypertension Society protocol were recruited among those attending our out-patient clinic.

Regression of left ventricular hypertrophy and cardiovascular risk changes in hypertensive patients.

Hypertensive left ventricular hypertrophy (LVH) may be detected in about one third of people with hypertension. When an individual with elevated blood pressure develops LVH, the risk of adverse cardiovascular events in the ensuing years almost doubles even in the absence of symptoms. Because of this high added risk, hypertension and other modifiable risk factors should be managed aggressively with lifestyle measures and drugs.

Validation of the A&D UA-774 (UA-767Plus) device for self-measurement of blood pressure.

Objectives: To determine the accuracy of the UA-774 (UA-767Plus) blood pressure monitor developed by the A&D Company.

Methods: Device evaluation was performed according to the modified British Hypertension Society (BHS) protocol released in 1993. Eighty-five subjects with characteristics outlined in the BHS protocol were recruited among those attending the outpatient clinic of the Department of Cardiovascular Disease, Hospital 'R.