Publications by authors named "Loretta Biserna"

Asthma is the most frequent chronic disease of childhood, affecting up to 20% of children worldwide. The main guidelines on asthma maintenance therapy in pediatrics suggest different approaches and describe different stages of asthma to determine the most appropriate treatment. This project aims to summarize the most recent evidence regarding maintenance therapy for asthma in children and adolescents.

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Article Synopsis
  • Wheezing is common in preschoolers, affecting about 30% of children under three, and these children face significantly higher rates of emergency visits and hospitalizations compared to older kids with asthma.
  • A consensus document from experts in Italy outlines mechanisms behind preschool wheezing, identifying both risk factors (like allergies, pollution, and tobacco exposure) and protective factors (such as breastfeeding and vitamin D).
  • The expert panel used systematic reviews and the GRADE approach to develop recommendations, emphasizing the need for more research and preventive strategies to reduce children's exposure to risks that harm respiratory health.
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Preschool wheezing should be considered an umbrella term for distinctive diseases with different observable and measurable phenotypes. Despite many efforts, there is a large gap in knowledge regarding management of preschool wheezing. In order to fill this lack of knowledge, the aim of these guidelines was to define management of wheezing disorders in preschool children (aged up to 5 years).

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Bronchial asthma is the most frequent chronic disease in children and affects up to 20% of the pediatric population, depending on the geographical area. Asthma symptoms vary over time and in intensity, and acute asthma attack can resolve spontaneously or in response to therapy. The aim of this project was to define the care pathway for pediatric patients who come to the primary care pediatrician or Emergency Room with acute asthmatic access.

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A healthy 16-year-old boy was hospitalized for fever, septic condition and thrombosis of the left internal jugular vein: The diagnosis of Lemierre syndrome (LS) with positive blood culture for Fusobacterium necrophorum was formalized. He was treated with antibiotics and anticoagulant therapy with enoxaparin with complete recovery. Four weeks after discharge, the jugular vein ecodoppler showed complete resolution of the thrombosis.

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