Comparison of plasma concentrations of levobupivacaine with and without epinephrine for transversus abdominis plane block.

Background And Objectives: The pharmacokinetics for levobupivacaine in transversus abdominis plane (TAP) blocks has not been previously reported. We aimed to determine the extent of the block and the effect on plasma concentrations of levobupivacaine with the addition of epinephrine.

Methods: We enrolled 11 healthy volunteers in this double-blind, 2-intervention, 2-period crossover study.