Publications by authors named "Lorenzo Manelli"
Article Synopsis
- * Cardiovascular magnetic resonance (CMR) imaging is crucial for assessing TS, as it can noninvasively identify distinct heart tissue characteristics and abnormalities related to the condition.
- * Recent advances in CMR techniques are enhancing its role in diagnosing, predicting outcomes, and managing TS, with a focus on new biomarkers that improve accuracy and patient care.
Importance: Guidelines for clinical management in Li-Fraumeni syndrome, a multiple-organ cancer predisposition condition, are limited. Whole-body magnetic resonance imaging (WBMRI) may play a role in surveillance of this high-risk population.
Objective: To assess the clinical utility of WBMRI in germline TP53 mutation carriers at baseline.