Simultaneous ultrasound assessment of brachial artery shear stimulus and flow-mediated dilation during reactive hyperemia.

In flow-mediated dilation (FMD) studies, brachial artery diameter changes due to reactive hyperaemia are typically measured through manual or automatic analysis of high resolution B-mode images while the stimulus of diameter change, i.e., the flow change, is qualitatively estimated by measuring the mean velocity in the vessel and assuming a parabolic velocity profile.

An automatic angle tracking procedure for feasible vector Doppler blood velocity measurements.

Two-dimensional angle-independent blood velocity estimates typically combine the Doppler frequencies independently measured by two ultrasound beams with known interbeam angle. A different dual-beam approach was recently introduced in which one (reference) beam is used to identify the flow direction, and the second (measuring) beam directly estimates the true flow velocity at known beam-flow angle. In this paper, we present a procedure to automatically steer the two beams along optimal orientations so that the velocity magnitude can be measured.

Accuracy and reproducibility of a novel dual-beam vector Doppler method.

Conventional Doppler ultrasound (US) investigations are limited to detect only the axial component of the blood velocity vector. A novel dual-beam method has been recently proposed in which the Doppler angle is estimated through a reference US beam, and the velocity magnitude through a measuring US beam, respectively. In this study, the performance of such a method has been assessed quantitatively through in vitro and in vivo measurements made in different experimental conditions.