Publications by authors named "Lorenzo De Luca"
Advances in medical and surgical interventions have resulted in a steady increase in the number of patients with congenital heart disease (CHD) reaching adult age. Unfortunately, this ever-growing population faces an added challenge: an increased risk of acquiring coronary artery disease. This review provides insight into the complex interactions between coronary artery disease and CHD in adults.
View Article and Find Full Text PDFEdible flowers are regaining interest among both the scientific community and the general population, not only for their appealing sensorial characteristics but also from the growing evidence about their health benefits. Among edible flowers, those that contain anthocyanins are among the most consumed worldwide. However, little is known regarding the bioaccessibility and absorption of their bioactive compounds upon ingestion.
View Article and Find Full Text PDFBiallelic truncating variants in children with titinopathy represent a recognizable condition with distinctive muscular and cardiac characteristics: a report on five patients.
Front Cardiovasc Med
July 2023
Article Synopsis
- This study investigates the connection between biallelic truncating variants and various musculoskeletal and cardiac disorders in children, emphasizing the limited understanding of cardiac issues associated with these variants in the pediatric population.
- Five pediatric patients with biallelic variants were reviewed, showing severe musculoskeletal problems (arthrogryposis multiplex) and significant cardiac issues, including dilated cardiomyopathy and congenital heart defects, with most patients diagnosed early in life.
- The findings suggest that biallelic variants should be considered in children displaying severe, early-onset dilated cardiomyopathy and skeletal abnormalities, as these conditions are often linked to end-stage heart failure, which may necessitate heart transplantation.
The abdominal aortic aneurysm (AAA) is a potentially fatal asymptomatic disease. It progresses silently with clinical complications that, when they occur, constitute a very serious event, frequently resulting in the patient's exitus. As a result, early detection and treatment are critical because the right therapeutic strategy can halt the disease's natural progression.
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