Publications by authors named "Lorene M Yoxtheimer"
Article Synopsis
- The study evaluates how preanalytic variables, like cellularity and storage time, influence the quality and quantity of nucleic acids extracted from thyroid fine-needle aspiration specimens.
- Data from 56 samples showed a correlation between the Bethesda classification of nodules and cellularity, along with variations in nucleic acid concentrations based on storage duration.
- The findings indicate that higher cellularity generally yields better quality nucleic acids, and prolonged storage may negatively impact DNA and RNA integrity, suggesting a need for further research into these factors.
Background: Homeobox transcription factors have demonstrated utility in diagnosing neuroendocrine tumors. Orthopedia homeobox protein (OTP) has a well-defined role in embryonic neurodevelopment and has also been described as a prognostic marker in lung neuroendocrine tumors (NET). Additionally, NK6 homeobox-1 (NKX6.
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