Laryngotracheal Complications after Intubation for COVID-19: A Multicenter Study.

Unlabelled: Many of the patients with COVID-19 have suffered respiratory distress requiring prolonged endotracheal intubation (ETI) resulting in laryngotracheal complication with an impact on breathing, phonation, and swallowing. Our aim is to describe laryngeal injuries diagnosed after ETI in patients with COVID-19 in a multicentre study.

Methods: A prospective descriptive observational study was conducted from January 2021 to December 2021, including COVID-19 patients with laryngeal complications due to ETI diagnosed in several Spanish hospitals.

Kaolin particle films disrupt landing, settling behavior and feeding of Trioza erytrae on lemon plants.

Background: The citrus greening disease or Huanglongbing (HLB) is the most devastating disease of citrus crops. Trioza erytreae is a vector of HLB. Since its introduction in Europe, the insect reached the northern region of Spain and the southern region of Portugal, threatening relevant citrus production areas.

E-cadherin downregulation sensitizes PTEN-mutant tumors to PI3Kβ silencing.

Alterations in phosphatidylinositol 3-kinase (PI3K) and in PTEN (phosphatase and tensin homolog), the negative regulator of the PI3K pathway, are found in nearly half of human tumors. As PI3Kβ, the main isoform activated in PTEN-mutant tumors, has kinase-dependent and -independent activities, we compared the effects of depleting vs. drug-inhibiting PI3Kβ kinase activity in a collection of diverse tumor types and in a set of bladder carcinoma cell lines grown as xenografts in mice.

Development and validation of a short version of the Spanish pediatric voice handicap index (P-VHI-10).

Objectives: A child's voice is used both as a tool for communication and as a form of emotional expression. Thus, voice disorders suffered by children have negative effects on their quality of life, which can be assessed using the "Pediatric Voice Handicap Index" (P-VHI). This questionnaire is completed by the parents of dysphonic patients and it has been validated in different languages: Italian, Korean, Arabic, and Spanish.

Adaptation and validation of Spanish version of the pediatric Voice Handicap Index (P-VHI).

Objectives: The voice in childhood is a communication tool and a form of emotional expression. It is estimated that 6 to 23% of children may have voice disorders. There is a test, the Pediatric Voice Handicap Index (P-VHI), validated in English to assess the specific impact on quality of life of children with speech pathology.

Corrigendum to: Swept-sine noise-induced damage as a hearing loss model for preclinical assays.

[This corrects the article on p. 7 in vol. 7, PMID: 25762930.

Current indications for the osteoplastic flap.

Introduction And Objectives: Endoscopic sinus surgery is the technique of choice in most of the frontal sinus diseases, both inflammatory and tumour-related. This is why the external approach using osteoplastic flap (OF) would be limited to cases with a difficult endoscopic approach. Our aim was to review the current indications of the osteoplastic flap in the treatment of frontal sinus pathology, through a retrospective study of patients undergoing this technique.

Swept-sine noise-induced damage as a hearing loss model for preclinical assays.

Mouse models are key tools for studying cochlear alterations in noise-induced hearing loss (NIHL) and for evaluating new therapies. Stimuli used to induce deafness in mice are usually white and octave band noises that include very low frequencies, considering the large mouse auditory range. We designed different sound stimuli, enriched in frequencies up to 20 kHz ("violet" noises) to examine their impact on hearing thresholds and cochlear cytoarchitecture after short exposure.

Drug delivery to the inner ear: strategies and their therapeutic implications for sensorineural hearing loss.

Hearing aids or cochlear implants constitute almost exclusively the treatment options currently available to patients suffering from sensorineural hearing loss and related conditions, such as noise-induced hearing loss, ototoxicity or autoimmune inner ear disease. While some systemic treatments exist, they generally exert adverse secondary effects and their efficacy is hampered by the blood-cochlear barrier that limits drug access to the inner ear. Hence, the new therapies that are being developed for hearing loss focus on strategies for direct drug delivery to the inner ear.

[Correlation between active anterior rhinomanometry and nasal endoscopy].

Objective: Nasal permeability is related to functional and anatomical parameters, which are objectified by active anterior rhinomanometry (AARNM). The study aims to compare alterations visualized through Nasal Endoscopy (NE) with nasal flow parameters in AARNM.

Material And Methods: We carried out a prospective observational study of 45 patients suffering from nasal obstruction and septal deviation.

[Musical perception and enjoyment in post-lingual patients with cochlear implants].

Objectives: To evaluate music perception and enjoyment following cochlear implantation and its impact on quality of life (QOL).

Material And Method: Eighty-eight adult post-lingually deaf cochlear implant users entered the study. The music questionnaire analyzed musical background, listening habits, and quality of musical sound through the cochlear implant.

Changes in listening habits and quality of musical sound after cochlear implantation.

Objective: To evaluate listening habits and quality of musical sound after cochlear implantation.

Study Design: A total of 89 consecutive, adult, postlingually deafened, cochlear implant recipients entered the study. Music questionnaire included questions about musical background, listening habits, and quality of musical sound through cochlear implants.