Endothelial dysfunction in children with chronic kidney disease.

Background And Objective: Cardiovascular disease (CVD) is the main cause of death in children with chronic kidney disease (CKD). Inflammation and endothelial dysfunction (ED) are found in the majority of these patients and are factors associated to CVD. Flow mediated dilatation (FMD) is a surrogate marker validated for evaluating ED.

Factors That Influence the Attitude of the Population to Be a Donor in Mexico.

Background: Transplantation depends on a donation from a living or deceased donor, with the latter ideally involving a multiorgan transplant. The objective of this study was to determine the factors that influence the attitudes of the population in Mexico toward being a donor.

Methods: We conducted an observational, cross-sectional study with a survey on the attitudes toward donation in the population of Mexico.

Carotid intima media thickness, oxidative stress, and inflammation in children with chronic kidney disease.

Objective: We evaluated the association between inflammation and oxidative stress with carotid intima media thickness (cIMT) and elasticity increment module (E(inc)) in pediatric patients with chronic kidney disease (CKD).

Methods: This analytical, cross-sectional study assessed 134 children aged 6-17 years with CKD. Anthropometric measurements and biochemistry of intact parathyroid hormone (iPTH), high-sensitivity C-reactive protein (CRP), interleukin (IL)-6, IL-1β, reduced glutathione (GSH), malondialdehyde, nitric oxide, and homocysteine were recorded.

Impact of global economic disparities on practices and outcomes of chronic peritoneal dialysis in children: insights from the International Pediatric Peritoneal Dialysis Network Registry.

Unlabelled: BACKGROUND, OBJECTIVES, AND METHODS: The number of patients on chronic peritoneal dialysis (CPD) is increasing rapidly on a global scale. We analyzed the International Pediatric Peritoneal Dialysis Network (IPPN) registry, a global database active in 33 countries spanning a wide range in gross national income (GNI), to identify the impact of economic conditions on CPD practices and outcomes in children and adolescents.

Results: We observed close associations of GNI with the fraction of very young patients on dialysis, the presence and number of comorbidities, the prevalence of patients with unexplained causes of end-stage kidney disease, and the rate of culture-negative peritonitis.

Frequency of low carnitine levels in children on dialysis.

To determine the frequency of low carnitine levels, we measured serum carnitine in pediatric patients on peritoneal dialysis (PD) and hemodialysis (HD). Our prospective cross-sectional study was conducted from September 2004 to March 2005 in a single pediatric center, and included patients under 17 years of age who had been on HD or PD for more than 3 months. Patients with primary carnitine deficiency were excluded.