Publications by authors named "Lorena Guzman"

Objective: To evaluate long-term prognosis in patients with refractory status epilepticus according to the level of sedation reached during drug-induced coma.

Materials And Methods: Longitudinal study of patients with status epilepticus who received anesthetics to induce therapeutic coma. Demographic data, clinical, and electroencephalographic characteristics were collected, as well as variables related to sedation.

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Objective: The aim of this study was to evaluate the efficacy, tolerability, and retention of brivaracetam (BRV) in genetic generalized epilepsy (GGE) in real-life practice.

Methods: This is a retrospective cohort study of adult patients with GGE in whom BRV was started between 2016 and 2018, completing a follow-up period of ≥6 months. Clinical and electroencephalogram (EEG) characteristics were analyzed at baseline and at follow-up as outcome measures.

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Objective: To evaluate the perfusion computed tomography (PCT) patterns in patients with status epilepticus (SE).

Methods: We included consecutive SE patients, diagnosed by ictal encephalography (EEG) findings and clinical semiology, who prospectively underwent a dedicated PCT study of SE in the ictal phase. The perfusion maps were visually analyzed.

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Purpose: The risk of developing epilepsy at long term after post-stroke status epilepticus (PSSE) is unknown. We aimed to evaluate post-stroke epilepsy (PSE) after early-onset PSSE and its associated factors.

Method: All consecutive patients with early-onset PSSE and no history of epilepsy admitted to our hospital between February 2011 and April 2017 were included.

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To our knowledge, there are no reports of status epilepticus (SE) associated with mitochondrial diseases and treated with perampanel (PER). We present three cases of patients with refractory SE associated with MELAS syndrome who responded favorably to PER. All cases were diagnosed as non-convulsive SE (focal without impairment of level of consciousness).

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Purpose: This study aimed to investigate the prognosis of patients with status epilepticus (SE) following stroke, focusing on the timing of SE after the event and other unexplored variables.

Methods: All consecutive patients experiencing post-stroke SE (PSSE) in our center were included (2011-2016). We analyzed SE- and stroke-related factors in relation to the patients' outcome.

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Purpose: There is concern about the safety of anesthetic drugs (IVADs) in the management of status epilepticus (SE). To clarify this aspect, we aimed to assess the factors associated with a poor prognosis in SE requiring anesthetics.

Method: We analyzed all SE requiring IVADs between October 2011 and December 2015.

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Article Synopsis
  • Doctors are finding it hard to figure out the best way to treat a condition called hypoxic myoclonic status, but cooling the body down might help some patients.
  • A new medicine called perampanel (PER) has been tested and showed good results in one patient who had severe myoclonic issues after a heart-related emergency.
  • The case suggests that PER could be a helpful choice for treating this serious condition, possibly even before using harsher treatments that can cause more problems.
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