Beyond-use dating of lidocaine alone and in two "magic mouthwash" preparations.

Purpose: Beyond-use dating (BUD) of lidocaine alone and in two "magic mouthwash" preparations stored in amber oral syringes at room temperature was determined.

Methods: Two formulations of mouthwash containing oral topical lidocaine 2% (viscous), diphenhydramine 2.5 mg/mL, and aluminum hydroxide-magnesium hydroxide-simethicone were prepared in 1:1:1 and 1:2.

Beyond-use date determination of buprenorphine buccal solution using a stability-indicating high-performance liquid chromatographic assay.

Objectives: The objectives of this study included developing and validating a stability-indicating high-performance liquid chromatographic (HPLC) method with ultraviolet (UV) detection for the determination of buprenorphine in a buccal solution for veterinary use, and applying that method to determine the stability of a 3 mg/ml buprenorphine preparation in room temperature and refrigerated storage conditions. This preparation, intended for buccal administration in feline patients, plays an important role in pain management in cats.

Methods: A stability-indicating HPLC method was developed and validated for system suitability, accuracy, repeatability, intermediate precision, specificity, linearity and robustness based on US Pharmacopeia (USP) General Chapter <1225>.

Effects of compounding and storage conditions on stability of pergolide mesylate.

Objective: To determine the effects of temperature and light over a 35-day period on stability of pergolide mesylate after compounding in an aqueous vehicle.

Design: Evaluation study.

Procedures: Pergolide was compounded into a formulation with a final target concentration of 1 mg/mL.

Golden Ticket to the United States Pharmacopeial Convention's Veterinary Internship.

The future of the United States Pharmacopeial's impact on a broad spectrum of entities, including healthcare professionals, government agencies, and academic organizations, is expanding. The organization's outreach programs, like the summer internship opportunity, are influencing young professionals from a variety of specialties and interests. It broadens the view of the student to include pharmacy practice, policy issues, the superfluity of opportunities, and specialized careers in the healthcare industry.