Hepatitis E Virus (HEV) Infection Among Immunocompromised Individuals: A Brief Narrative Review.

Hepatitis E virus (HEV) is a single-stranded positive-sense RNA virus that belongs to family. HEV is the most common cause of acute viral hepatitis worldwide. According to the World Health Organization (WHO), there are estimated 20 million HEV infections worldwide every year, leading to estimated 3.

Homo- and heterometallic complexes of Zn(II), {Zn(II)Au(I)}, and {Zn(II)Ag(I)} with pentadentate Schiff base ligands as promising anticancer agents.

Two families of homo- and heterometallic complexes, [ZnL(μ-OH)(HO)](ClO), [ZnL(μ-OH)(HO)](ClO), [ZnL(μ-OH)(HO)](ClO), 1∞[{LZn(μ-OH)}{μ-[Ag(CN)]}](ClO), [{LZn(μ-OH)}{μ-[Au(CN)]}{[Au(CN)]}](ClO)·HO, 1∞[{LZn(μ-OH)}(HO){μ-[Ag(CN)]}](ClO)·THF·0.5MeOH, 1∞[{LZn(μ-OH)}(HO){μ-[Au(CN)]}](ClO)·THF·HO, and 1∞[{LZn(μ-OH)}{μ-[Ag(CN)]}][Ag(CN)]·HO, respectively, have been synthesized and characterized. The Schiff bases used as ligands were obtained by condensation reactions of 2,6-diformyl--cresol with ,-dimethyl-ethylenediamine (HL), 2-aminomethyl-pyridine (HL), and 2-aminoethyl-pyridine (HL), respectively.

Metal Zn(II), Cu(II), Ni (II) complexes of ursodeoxycholic acid as putative anticancer agents.

The aim of the study was to evaluate the influence of metal [Zn(II), Cu(II), Ni(II)] complexes with ursodeoxycholic acid (UDCA) on the viability and proliferation of tumour and non-tumour cells. Cell lines established from retrovirus-transformed chicken hepatoma (LSCC-SF-Mc29) and rat sarcoma (LSR-SF-SR) as well as from human cancers of the breast (MCF-7), uterine cervix (HeLa), lung (A549) and liver (HepG2) were used as model systems. Non-tumour human embryo (Lep-3) cells were also included in some of the experiments.