Publications by authors named "Lopez-Serrano P"

Background: Seedling growth and survival depend on seedling quality. However, there is no experimental evidence showing that the seedling dimensions of the abundant, economically important and widely distributed tree species , , , , and and their hybrids effectively improve survival and growth in reforestations and plantations in Mexico. Therefore, the aim was to evaluate the influence of initial morphological parameters of 2,007 nursery seedlings of these species and their hybrids on their growth and survival 44 months after planting in the Sierra Madre Occidental, Mexico.

View Article and Find Full Text PDF
Article Synopsis
  • Ustekinumab is approved for treating ulcerative colitis (UC), and this study evaluated its long-term effectiveness and tolerability in real clinical settings.
  • In a multicenter analysis of 620 UC patients, 25% discontinued treatment, with baseline anemia, steroid use, and severe disease linked to higher discontinuation rates.
  • At 16 weeks, 40% of patients were in steroid-free remission, and treatment was generally safe with no adverse effects on other conditions, indicating good long-term durability for difficult-to-treat cases.
View Article and Find Full Text PDF

Background And Objectives: inflammatory bowel disease (IBD) has a major impact on psychological well-being. This condition is associated with a high level of anxiety and mood disorders, but stress prevalence and how an individual copes with IBD have not been sufficiently explored. The objective of this study was to assess the impact of the disease on psychological disorders and to identify coping strategies used by patients with IBD, as well as to analyze the relationship between these variables and sociodemographic and clinical variables.

View Article and Find Full Text PDF
Article Synopsis
  • - Cervical cancer is the fourth most prevalent cancer in women globally, with a significant risk among those who are immunosuppressed, particularly due to AIDS or organ transplants, as they struggle to clear persistent HPV infections.
  • - European guidelines suggest that women with inflammatory bowel disease (IBD) who are on immunosuppressive therapy should be screened for cervical cancer as frequently as other high-risk groups, though solid evidence supporting this practice is lacking in Spain.
  • - A study conducted from 2020-2021 at a Spanish university hospital analyzed risk factors for low-grade and high-grade cervical lesions in women with IBD, comparing patients with cervical abnormalities to a control group and exploring their disease characteristics, treatment histories, and
View Article and Find Full Text PDF

Forest plantations and natural forests perform a relevant role in capturing CO and reducing greenhouse gas concentrations. The objective of this study was to compare the diameter increment, biomass and carbon accumulation in a plantation of and a naturally regenerated stand. The data were collected from 32 circular plots of 100 m (16 plots in the planted site and 16 in naturally regenerated area).

View Article and Find Full Text PDF

Agave lechuguilla Torr., of the family Agavaceae, is distributed from southwestern United States to southern Mexico and is one of the most representative species of arid and semiarid regions. Its fiber is extracted for multiple purposes.

View Article and Find Full Text PDF
Article Synopsis
  • The latitudinal diversity gradient (LDG) reflects a global trend showing that species richness typically increases towards the tropics, but understanding its causes has been challenging due to insufficient data.
  • A new high-resolution map of local tree species richness was created using extensive global forest inventory data and local biophysical factors, analyzing around 1.3 million sample plots.
  • Findings indicate that annual mean temperature is a significant predictor of tree species richness, aligning with the metabolic theory of biodiversity, but additional local factors also play a crucial role, especially in tropical regions.
View Article and Find Full Text PDF

Background And Aims: Clinical trials and real-life studies with ustekinumab in Crohn's disease [CD] have revealed a good efficacy and safety profile. However, these data are scarcely available in elderly patients. Therefore, we aim to assess the effectiveness and safety of ustekinumab in elderly patients with CD.

View Article and Find Full Text PDF

Background: Optimal golimumab concentration thresholds for important outcomes during maintenance are lacking.

Aims: To investigate the association of golimumab trough concentrations during maintenance with key outcomes, including endoscopic and histologic remission, and long-term event-free persistence with golimumab, in patients with UC.

Methods: This multi-centre, cross-sectional study included patients with UC on golimumab maintenance recruited either in remission or during a flare.

View Article and Find Full Text PDF

(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year.

View Article and Find Full Text PDF

Background And Aims: The development programm UNIFI has shown promising results of ustekinumab in ulcerative colitis [UC] treatment which should be confirmed in clinical practice. We aimed to evaluate the durability, effectiveness, and safety of ustekinumab in UC in real life.

Methods: Patients included in the prospectively maintained ENEIDA registry, who received at least one intravenous dose of ustekinumab due to active UC [Partial Mayo Score [PMS]>2], were included.

View Article and Find Full Text PDF

Background: A significant percentage of patients treated with ustekinumab may lose response. Our aim was to evaluate the short-term efficacy and safety of intravenous re-induction with ustekinumab in patients with Crohn's disease who have lost the response to the treatment.

Methods: This is a retrospective, observational, multicenter study.

View Article and Find Full Text PDF

The COVID-19 pandemic has forced major changes in the care of patients with inflammatory bowel disease (IBD). The articles by El Hajra et al. and Fernández Álvarez el al.

View Article and Find Full Text PDF

Purpose: biosimilar infliximab (CTP-13) has been recently approved for the treatment of several immune-mediated inflammatory disorders, including inflammatory bowel disease (IBD). Comparative studies between this biosimilar and original infliximab in the real clinical practice are scarce. The objective of this study was to compare short and long-term safety and efficacy of original (O) and biosimilar infliximab (B-IFX) in biologic-naïve, IBD patients in the real life clinical practice.

View Article and Find Full Text PDF

Introduction: Patients with Crohn's disease experiencing endoscopic postoperative recurrence (POR) may benefit from antitumor necrosis factor (TNF) agents but scarce data on this are available. Our aim was to assess the efficacy of anti-TNF in improving mucosal lesions in patients with endoscopic POR.

Methods: Multicenter, retrospective, study of patients with Crohn's disease who underwent therapy with anti-TNF agents for endoscopic POR (Rutgeerts score > i1).

View Article and Find Full Text PDF

Autoimmune liver diseases can overlap resulting in a new entity, phenotypically different from those pathologies that converge, and that demonstrates the complexity of our immune system. Sequential overlap syndrome is the consecutive presentation, separated by a variable period of time, of two liver autoimmune diseases, mostly autoimmune hepatitis and primary biliary cholangitis. This syndrome constitutes a challenge both in its diagnosis and in its treatment given the exceptional nature of its presentation.

View Article and Find Full Text PDF

Identifying the relative importance of human and environmental drivers on fire occurrence in different regions and scales is critical for a sound fire management. Nevertheless, studies analyzing fire occurrence spatial patterns at multiple scales, covering the regional to national levels at multiple spatial resolutions, both in the fire occurrence drivers and in fire density, are very scarce. Furthermore, there is a scarcity of studies that analyze the spatial stationarity in the relationships of fire occurrence and its drivers at multiple scales.

View Article and Find Full Text PDF

Blue rubber bleb nevus syndrome (BRBNS) is a rare disorder with characteristic skin hemangiomas and vascular malformations, mostly in the gastrointestinal (GI) tract. The GI lesions are mainly located in the stomach and small intestine, usually more than a hundred, leading to gastrointestinal bleeding and severe chronic anemia. Parenteral iron infusions and scheduled transfusions are frequently necessary.

View Article and Find Full Text PDF
Article Synopsis
  • Primary sclerosing cholangitis (PSC) is often linked with inflammatory bowel disease (IBD) and is associated with a higher risk of cancers, especially colorectal cancer (CRC) and cholangiocarcinoma (CCA).
  • A study of 277 PSC-IBD patients revealed a PSC incidence rate of 61 cases per 100,000 IBD patient-years, with the majority treated using ursodeoxycholic acid and some requiring liver transplants.
  • The findings indicate that PSC symptoms at diagnosis increase CRC risk, with CCA found primarily in patients with intra- and extrahepatic PSC, leading to poorer survival compared to those without CCA.
View Article and Find Full Text PDF

Aim: To assess the likelihood of detecting latent tuberculosis infection [LTBI] by the positive conversion of a serial tuberculin skin test [TST] at 1 year in inflammatory bowel disease [IBD] patients with negative baseline two-step TST.

Methods: In this multicentre prospective cohort study, we evaluated rate and predictors of conversion of TST at 1 year in patients with negative baseline TST. We also evaluated management of patients who had a positive TST at baseline or a conversion at 1 year.

View Article and Find Full Text PDF

Objectives: The long-term safety of exposure to anti-tumor necrosis factor (anti-TNFα) drugs during pregnancy has received little attention. We aimed to compare the relative risk of severe infections in children of mothers with inflammatory bowel disease (IBD) who were exposed to anti-TNFα drugs in utero with that of children who were not exposed to the drugs.

Methods: Retrospective multicenter cohort study.

View Article and Find Full Text PDF