Publications by authors named "Lopez-Castroman J"
Article Synopsis
- Internet-based psychological interventions offer accessible mental health care, addressing barriers like distance, cost, and safety, but research on their effects on biomarkers is limited.
- This systematic review examines how these interventions impact biomarkers across various clinical and nonclinical populations, with a secondary focus on whether changes in biomarkers relate to improvements in psychological or physical symptoms.
- Out of 24 studies analyzed, a diverse range of participants included those with psychiatric issues, medical diseases, and nonclinical individuals, indicating some effectiveness of cognitive behavioral therapy (CBT) in reducing certain biomarkers.
Obsessive-compulsive disorder (OCD) is a frequent and disabling condition, with many patients being treatment-resistant. Improved understanding of its neurobiology is vital for better therapies. Evidence is still conflicting regarding specific serotonergic-related dysfunctions in OCD.
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- The study focuses on early diagnosis challenges of ADHD and evaluates how parents and teachers assess children's behavior using the Behavior Rating Inventory of Executive Function-2 (BRIEF-2).
- Involving 59 mothers, 59 fathers, and 57 teachers, the research tested feature selection techniques to analyze their responses, determining that Lasso is the most effective method for data analysis.
- Results show a strong correlation (over 0.5) between reported inattention/hyperactivity and Lasso predictions, using only 18% of BRIEF-2 items, highlighting the method's efficiency in understanding ADHD in time-saving scenarios.
Systematic review of patient contribution to the development of alcohol craving measurements.
Alcohol Clin Exp Res (Hoboken)
September 2024
Article Synopsis
- Craving is a key symptom of alcohol or substance use disorders, but there’s no universal agreement on what drives it, and it must be self-reported by individuals.
- A systematic review of instruments measuring alcohol craving from 2012 to 2023 found that only one out of 16 identified instruments included patient input in its development, highlighting a lack of strong patient involvement in creating these assessment tools.
- None of the analyzed instruments fully met developmental quality criteria, with the majority being classified as either "inadequate" or "doubtful," indicating a need for better tools to assess alcohol craving effectively.
Article Synopsis
- * The study followed the PRISMA-ScR checklist, extracting data from 197 relevant papers published from 2000 to 2022, and categorized the reasons for euthanasia requests along with contextual factors like legality and human development index.
- * Findings revealed that the most common conditions leading to euthanasia requests included terminal cancer (45.4%), Alzheimer's and dementia (19.8%), severe physical or mental suffering (19.8%), treatment-resistant mood disorders (12.2%), and advanced cardiovascular diseases (12.
Purpose Of Review: Review the current evidence on biomarkers for bipolar disorder in the older adults. We conducted a systematic search of PubMed MEDLINE, PsycINFO, and Web of Science databases using the MeSH search terms "Biomarkers", "Bipolar Disorder", "Aged" and and "Aged, 80 and over". Studies were included if they met the following criteria: (1) the mean age of the study population was 50 years old or older, (2) the study included patients with bipolar disorder, and (3) the study examined one type of biomarkers or more including genetic, neuroimaging, and biochemical biomarkers.
View Article and Find Full Text PDFIntroduction: The Conners Scale for Parents (CRS-P) is one of the reference tools for the diagnostic assessment of Attention Deficit and Hyperactivity Disorders (ADHD). It is commonly used in both research and clinical practice. The latest edition of the Conners Parents Scale Long Version (CRS-P3L) has undergone extensive modifications but has never been compared with the 2nd edition (CRS-P2L).
View Article and Find Full Text PDFObjective: Hippocampal volume (HV) is a key imaging marker to improve Alzheimer's disease risk prediction. However, longitudinal studies are rare, and hippocampus may also be implicated in the subtle aging-related cognitive decline observed in dementia-free individuals. Our aim was to determine whether HV, measured by manual or automatic segmentation, is associated with dementia risk and cognitive decline in participants with and without incident dementia.
View Article and Find Full Text PDFThe high mortality rate in nursing homes during the COVID-19 pandemic may be linked to psychological disorders in staff. Hence, we assessed the prevalence and associated factors of probable post-traumatic stress disorder (PTSD), anxiety, depression, and burnout of nursing home staff during the COVID-19 pandemic in a cross-sectional study including 66 randomly selected nursing homes in southern France. 537 of the contacted 3 821 nursing home workers (14.
View Article and Find Full Text PDFIntroduction: The prevalence of psychiatric disorders has not shifted widely through the COVID pandemic, except for some specific groups such as young people or women. Our objective is to examine prospectively the evolution of children and adolescents who consulted in a psychiatric emergency service during the COVID-19 confinements.
Method: We collected prospective clinical information about 296 young people under 18 who visited a tertiary hospital for psychiatric reasons during the confinement periods in Spain.