Bilateral alveolar rhabdomyosarcoma of breast: a rare entity.

Sarcomas of breast constitute less than 1% of all malignant breast tumours. Alveolar rhabdomyosarcoma (RMS) is very rare in breast with limited case reports in literature, and primary alveolar RMS arising from breast is still less common than metastatic RMS. Here, we report a case of primary bilateral alveolar RMS of breast in an adolescent female where the correct diagnosis was obfuscated by an overlap in the histological features of RMS and high-grade invasive ductal carcinoma.

Cutaneous melanoma in childhood presenting as intraparotid lymph node metastasis.

Cutaneous melanoma in childhood is a rare disease. Rendering a clinical diagnosis of melanoma in pediatric patients is confounded by the fact that pigmented lesions in pediatric patients do not conform to the ABCDE rules applicable to adult patients. Furthermore, making a histologic diagnosis of cutaneous melanoma in childhood is also difficult with no universally accepted criteria applicable to pediatric melanomas.

Dengue and Typhoid Co-infection- Study from a Government Hospital in North Delhi.

Background: Concurrent infection with two agents can result in an illness having overlapping symptoms creating a diagnostic dilemma for the treating physician. The symptoms of dengue may mimic other diseases such as leptospirosis, influenza A, Salmonella Typhi, Japanese encephalitis, chikungunya and malaria. There is paucity of data regarding dengue and typhoid co- infection both in the developed and developing countries.

Antimicrobial resistance in bacterial isolates from a delhi hospital: one year outcomes.

Antimicrobial resistance and hospital acquired infections have become an important public health issue. Data on pathogen and antibiotic resistance is important for physicians, microbiologists and infection control officials but limited information on antibiotic resistance prevents pathogen specific therapy and propels antibiotic misuse. A retrospective review of bacterial isolation and antimicrobial susceptibility profiles in the in- and outpatients of a Delhi hospital between January 2009-December 2009 was performed.

Molecular phenotypes of ductal carcinoma-in-situ and invasive ductal carcinoma: a comparative study.

Aims And Objectives: This study was aimed at analyzing the prevalence of molecular phenotypes in invasive ductal carcinoma (IDC) and coexisting ductal carcinoma-in-situ (DCIS) and to correlate with clinicopathological features.

Materials And Methods: In this study, 75 cases of IDC with coexisting DCIS were included. Molecular phenotype was determined using expression of estrogen receptor, progesterone receptor, HER2/neu, and cytokeratin 5/6.

Morphometric evaluation of megakaryocytes in bone marrow aspirates of immune-mediated thrombocytopenic purpura.

Immune-mediated thrombocytopenic purpura (ITP), one of the common causes of thrombocytopenia, is characterized by morphologic alterations in megakaryocytes in the bone marrow. Few studies have explored morphometric measurements of megakaryocytes in bone marrow trephine biopsies. Quantitative morphometric analysis of megakaryocytes in bone marrow aspirate smears is lacking in the available literature.

Tissue microarray construction from gross specimens: development of a novel simple technique.

Background: The tissue microarray (TMA) technique is becoming a useful tool for research and quality control methods in surgical pathology. However, the widespread use of this technique in routine surgical pathology practice, especially in developing nations, is hampered by the high cost of commercially available instruments. The authors describe a novel, inexpensive technique of construction of TMA from gross specimen.