Publications by authors named "Lopa Modi"
Article Synopsis
- The study investigates the correlation between ACR TI-RADS ultrasound scores and the risk of malignancy in cases with indeterminate thyroid fine needle aspiration cytology.
- A total of 46 cases were analyzed, revealing that most indeterminate cases had higher TI-RADS scores (TR4 and TR5) and that RAS mutations were the most common molecular alteration identified.
- The results suggest that while molecular testing is useful for TR4 and TR5 lesions, lower TI-RADS scores (TR2 and TR3) frequently showed no significant molecular changes, indicating the importance of ultrasound features in evaluating indeterminate cytology.
Article Synopsis
- The study analyzed changes in guidelines for reporting benign endometrial cells (BECs) in cervical cytology, specifically raising the reporting age from 40 to 45 years under the 2014 Bethesda System (TBS 2014).
- Researchers reviewed follow-up results of Papanicolaou tests in women aged 40 and older, finding that a significant portion showed benign results, particularly in younger age groups, with notable differences observed in women aged 50 and older.
- The findings support the justification for the TBS 2014 revision and suggest that an age threshold of 50 years may be more appropriate for reporting BECs than the current 45 years.
Article Synopsis
- The American College of Radiology (ACR) developed the Thyroid Imaging Reporting and Data System (TI-RADS) to improve thyroid ultrasound evaluations and predict the likelihood of cancer in thyroid nodules using a scoring system from TR1 to TR5 based on various ultrasound features.* -
- An analysis of 361 thyroid nodules with available ACR TI-RADS reports revealed that most nodules fell into the TR4 and TR3 categories, with no nodules classified as TR2 or TR3 corresponding to malignant cytology (Bethesda category VI).* -
- The study found a correlation between TI-RADS categories and cytology results, indicating that higher TI-RADS scores (TR4 and TR5) were associated
Objectives: Lymphovascular invasion (LVI) is a pathologic, microscopic finding associated with invasive cancer, and is a poor prognostic indicator, but has no reported imaging findings. This report presents the first documented case of LVI with seen by imaging. Linear branching microcalcifications were identified on mammography and clumped enhancement was noted on MRI, both imaging findings that are highly predictive of ductal carcinoma in situ (DCIS).
View Article and Find Full Text PDFTuberous sclerosis complex (TSC) and autosomal dominant polycystic kidney disease (ADPKD) are two diseases sharing close genetic loci on chromosome 16. Due to contiguous gene syndrome, also known as contiguous gene deletion syndrome, the proximity of TSC2 and PKD1 genes increases the risk of co-deletion resulting in a shared clinical presentation. Furthermore, Moyamoya disease (MMD) is a rare vaso-occlusive disease in the circle of Willis.
View Article and Find Full Text PDFBackground: Solid pseudopapillary tumor is a rare pancreatic neoplasm with uncertain to low malignant potential. This is an uncommon neoplasm with many pseudonyms, occurring predominantly in young woman under the age of thirty years.
Aims: To study the cytomorphological features of six cases of solid and pseudopapillary epithelial neoplasm of pancreas diagnosed on fine needle aspiration cytology (FNAC) in years 2005 to 2007 and its cyto-histological correlation.
Metastasis of mesothelioma of the pleura, to the skin and subcutis is an extremely rare occurrence. A 25 year old woman, who had undergone chemotherapy, partial excision of tumor followed by radiotherapy of sarcomatoid mesothelioma of the pleura, presented three months later with painless widespread subcutaneous nodules. FNAC of these nodules reveled pleomorphic malignant spindle shaped cell with epithelioid morphology.
View Article and Find Full Text PDF