Publications by authors named "Loosen J"

Background: Alzheimer's disease and related dementias (ADRD) patients who are hospitalized often develop oropharyngeal dysphagia, increasing risk for adverse outcomes, such as aspiration pneumonia. However, prevalence estimates of dysphagia are highly variable and often based on patient report or clinical testing rather than visualization of the swallow.

Objective: The aims of this study were to determine prevalence and severity of dysphagia among inpatients with ADRD referred for swallowing evaluation.

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Objective: Integration of patient-identified goals is a critical element of shared decision-making and patient-provider communication. There is limited information on the goals of patients with multiple medical conditions and high healthcare utilization. We aimed to identify and categorize the goals described by "high-need, high-cost" (HNHC) older patients and their caregivers.

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Objective: A literature review was conducted to examine how pharmacy students and technicians have been utilized in medication reconciliation processes in an effort to evaluate expanded roles for pharmacy students and technicians. Data were summarized on accuracy of obtaining medication histories, time requirements, discrepancy identification, and cost savings. Limitations and areas for future research also were identified.

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In a study using lateral cranial radiographs of 454 males and 475 females (age 0-20 years) the anterior nasal spine-nasion (ANS-N) and ANS-posterior nasal spine (ANS-PNS) distance were measured and related to age and gender. The development of both dimensions is best described by negative exponential functions. ANS-PNS distance to the age of 5 and the ANS-N distance to the age of 2, develop linearly without gender difference.

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Using a specially designed algorithm for the measurement of the surface area of shapes with highly irregular contours, growth curves were developed for post-natal septal growth in humans using post-mortem specimens of a study population of 30 cases, distributed over the age range from birth to 62 years. From the results a rapid growth phase for the total septum is evident immediately after birth, lasting until the second year of life. Then, a gradual deceleration of growth is recognized with a plateau eventually being reached at the age of 36 years.

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The ossification of the anterior skull base, especially the lamina cribrosa, has been studied by computed tomography and histopathology. Sixteen human fetuses, (referred to our laboratory for pathological examination after spontaneous abortion between 18 and 32 weeks of gestation) and three infants, (1, 2 and 6 years of age, respectively) were examined. The cartilaginous preformation of the anterior skull base creates a 'pseudo-defect' on CT in the coronal plane, even with ultra thin sections and high resolution CT.

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Magnetic Resonance Imaging (MRI) has been used for the characterization of human fetal nasal septa. The images were made from fixed fetal heads from spontaneous abortions of different gestational age. The "in-plane" resolution of the images (at a pixel size of 312 x 312 microns2) allowed a detailed anatomical analysis of the midfacial structures of the fetal heads.

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The largest part of the nasal septum in young children is cartilaginous. It was established that the cartilaginous septum shows a specific pattern of regional differences in thickness and histologic differentiation. The possible meaning of those phenomenons for growth and support are discussed.

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