Publications by authors named "Longteng Liu"
Insulin resistance is the primary contributor to the disruption in glucose homeostasis in the body, playing a significant causative role in many metabolic diseases. Insulin resistance is characterized by compensatory insulin secretion and reduced insulin responsiveness in target organs. Dysregulation of the interaction between insulin-secreting cells and insulin-responsive target organs is an important factor driving the progression of insulin resistance.
View Article and Find Full Text PDFThe mechanism of Girdin in degenerative brain disease caused by high glucose stimulation.
Front Endocrinol (Lausanne)
November 2022
Unlabelled: Girdin, as an actin-binding protein, plays a major role in maintaining the stability of the actin skeleton structure and affects the growth, development, and migration of neurons. This study discusses the mechanism of Girdin in brain degeneration caused by high glucose stimulation. We examined the expression of Girdin in diabetic patients.
View Article and Find Full Text PDFArticle Synopsis
- - A research study investigated the expression of the protein TPM2 in human atherosclerosis samples, using 34 clinical samples (17 with atherosclerosis and 17 normal arteries) collected over a few years.
- - Various techniques like immunohistochemistry and RT-qPCR were used to analyze TPM2 levels, revealing that its expression was significantly lower in atherosclerotic samples compared to normal arteries.
- - The findings suggest that TPM2 may serve as an independent protective factor for arteries and could be a new biomarker for atherosclerosis, with a significant correlation to the disease's progression (P<0.001).
Small-scale agriculture (SA) is regarded as unsustainability because of its low benefit. To protect traditional agricultural landscapes like terraces through SA will be difficult. However, in China, terraces are still maintained well by smallholders now.
View Article and Find Full Text PDFThe research of the possible mechanism and the treatment for capsaicin-induced cough.
Pulm Pharmacol Ther
April 2018
Unexplained chronic cough (UCC) affects millions of patients worldwide. New therapeutic approaches to this condition are urgently needed, since current treatment options provide only symptomatic relief. Cough reflex hypersensitivity has been shown to play an important role in the pathogenesis of UCC.
View Article and Find Full Text PDF[Expression of Girdin in brain tissues of Alzheimer's disease].
Zhonghua Bing Li Xue Za Zhi
May 2015
Objective: To investigate the expression of Girdin and its significance in Alzheimer's disease (AD).
Methods: Fifty-nine autopsy cases from Department of Pathology, Beijing Hospital from January 1988 to December 2013, including 35 AD cases and 24 non-AD cases as control. Girdin and amyloid β-protein (Aβ) expression was evaluated immunohistochemically by EnVision method.